Specialized Pharmaceutical Compositions for Cancer Treatment in Unique Operational Environments

Publication ID: 24-11857601_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Pharmaceutical Compositions for Cancer Treatment in Unique Operational Environments,” Published Technical Disclosure No. 24-11857601_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857601_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,601.

Summary of the Inventive Concept

The inventive concept adapts a pharmaceutical composition for cancer treatment, comprising a fusion protein including IL-2 protein and CD80 protein, and an anticancer drug, for specific, narrow markets or unique operational environments, such as high-security needs, disaster relief, or extreme weather conditions.

Background and Problem Solved

The original patent disclosed a pharmaceutical composition for cancer treatment comprising a fusion protein including IL-2 protein and CD80 protein, and an anticancer drug. However, the original patent did not address the need for specialized variations of this composition for use in unique operational environments, such as high-security facilities, disaster-stricken areas, or extreme weather conditions. The new inventive concept solves this problem by adapting the original composition for these specific contexts.

Detailed Description of the Inventive Concept

The new inventive concept comprises a system, method, or pharmaceutical composition that adapts the original composition for use in high-security environments, disaster relief, extreme weather conditions, remote areas, or high-altitude environments. For example, the system for treating cancer in a high-security environment includes a pharmaceutical composition with a fusion protein dimer comprising a CD80 protein and an IL-2 protein, and an anticancer agent, wherein the system is adapted for use in a biocontainment facility. The method for disaster relief comprises administering a pharmaceutical composition including a fusion protein dimer comprising a CD80 protein and an IL-2 protein, and an anticancer agent, to a patient in a disaster-stricken area, wherein the pharmaceutical composition is formulated for oral administration. The pharmaceutical composition for treating cancer in extreme weather conditions comprises a fusion protein dimer comprising a CD80 protein and an IL-2 protein, and an anticancer agent, wherein the pharmaceutical composition is packaged in a temperature-resistant container.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious compared to the original patent because it specifically addresses the need for specialized variations of the pharmaceutical composition for use in unique operational environments. The inventive concept's adaptation of the original composition for these specific contexts provides a new and unexpected solution to the problem of cancer treatment in these environments.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include adaptations for other unique operational environments, such as space exploration or military operations. Variations of the pharmaceutical composition could include different formulations or packaging designs tailored to specific environmental conditions.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical industry, particularly in the areas of cancer treatment and specialty pharmaceuticals. The target market includes healthcare providers, governments, and organizations operating in unique operational environments, such as high-security facilities, disaster relief organizations, and remote medical facilities.

CPC Classifications

SectionClassGroup
A A61 A61K38/2013
A A61 A61K31/337
A A61 A61K31/444
A A61 A61K31/4439
A A61 A61K31/47
A A61 A61K31/4709
A A61 A61K31/502
A A61 A61K31/506
A A61 A61K31/5025
A A61 A61K31/519
A A61 A61K31/708
A A61 A61K33/243
A A61 A61K38/1774
A A61 A61K39/3955
A A61 A61K45/06
A A61 A61P35/00

Field of Art

Pharmaceutical biotechnology, specifically cancer treatment compositions involving fusion proteins, immunomodulatory agents, and targeted drug delivery systems

Person of Ordinary Skill (PHOSITA) Profile

A biotechnology researcher with advanced degree (PhD/MD), expertise in protein engineering, immunology, and pharmaceutical formulation, familiar with cancer treatment strategies and protein modification techniques

Obviousness Rationale

A person having ordinary skill would recognize that adapting the source patent's pharmaceutical composition for specialized environmental conditions represents a predictable variation within standard pharmaceutical engineering practices. The core fusion protein technology remains consistent, with modifications focused on delivery, packaging, and contextual administration strategies. These variations would be considered routine optimization for pharmaceutical applications in challenging operational environments.

Obvious Combinations & Variations

Source Patent Element
Fusion protein dimer with CD80 protein and IL-2 variant for cancer treatment
PTD Variation
Adapting composition for biocontainment facility use with specialized packaging and administration protocols
Obviousness Reasoning
Standard pharmaceutical engineering practice involves developing environment-specific formulation strategies, which would be a predictable modification for a skilled practitioner
Source Patent Element
Anticancer agent combinations with fusion protein
PTD Variation
Formulating oral administration for disaster relief scenarios
Obviousness Reasoning
Modifying drug delivery method represents a known technique for expanding pharmaceutical utility in emergency medical contexts
Source Patent Element
Pharmaceutical composition with fusion protein and anticancer agents
PTD Variation
Temperature-resistant packaging for extreme weather conditions
Obviousness Reasoning
Developing robust pharmaceutical packaging is a well-established technique for ensuring drug stability across varied environmental conditions
Source Patent Element
Cancer treatment composition with immunomodulatory fusion protein
PTD Variation
High-altitude formulation compensating for immune system effects
Obviousness Reasoning
Adjusting pharmaceutical compositions for physiological variations is a standard approach in personalized medicine and targeted drug delivery
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the variations disclosed herein would be obvious to a person of ordinary skill in the art of pharmaceutical biotechnology, as exemplified by US Patent 11857601. The published technical disclosure demonstrates that the claimed variations represent predictable extensions of the source patent's core technological framework, employing standard engineering techniques to adapt the fundamental pharmaceutical composition for specialized operational contexts.

Original Patent Information

Patent NumberUS 11,857,601
TitlePharmaceutical composition for cancer treatment comprising fusion protein including IL-2 protein and CD80 protein and anticancer drug
Assignee(s)GI Innovation, Inc.