Personalized Cancer Treatment System with Targeted Fusion Protein and Anticancer Agent

Publication ID: 24-11857601_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Cancer Treatment System with Targeted Fusion Protein and Anticancer Agent,” Published Technical Disclosure No. 24-11857601_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857601_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,601.

Summary of the Inventive Concept

A next-generation cancer treatment system that combines a genetically engineered fusion protein dimer with a tailored anticancer agent, providing a personalized and targeted approach to cancer therapy.

Background and Problem Solved

The original patent disclosed a pharmaceutical composition for cancer treatment comprising a fusion protein dimer and an anticancer agent. However, this composition has limitations in terms of its generic approach to cancer treatment, lacking the ability to target specific cancer cells based on their genetic profile. The new inventive concept addresses this limitation by engineering the fusion protein dimer to target specific cancer cells and tailoring the anticancer agent to the specific genetic profile of the cancer cells.

Detailed Description of the Inventive Concept

The new inventive concept consists of a system for personalized cancer treatment, comprising a fusion protein dimer engineered to target specific cancer cells based on their genetic profile, and an anticancer agent tailored to the specific genetic profile of the cancer cells. The fusion protein dimer is designed to bind specifically to cancer cells with a particular genetic mutation, allowing for targeted delivery of the anticancer agent. The anticancer agent is selected based on the genetic profile of the cancer cells, ensuring maximum efficacy and minimal side effects. The system also includes a method for real-time monitoring of cancer treatment, allowing for adjustments to the dosage of the anticancer agent as needed.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious compared to the original patent, as it introduces a personalized and targeted approach to cancer treatment, using genetically engineered fusion protein dimers and tailored anticancer agents. The inventive step lies in the engineering of the fusion protein dimer to target specific cancer cells and the tailoring of the anticancer agent to the specific genetic profile of the cancer cells.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different types of fusion protein dimers, such as those engineered to target specific cancer stem cells or those conjugated to nanoparticles for targeted delivery. Variations could also include the use of different types of anticancer agents, such as immunotherapies or gene therapies.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in the field of cancer treatment, with a target market including pharmaceutical companies, hospitals, and research institutions. The system's ability to provide personalized and targeted cancer treatment could revolutionize the field of oncology, offering a more effective and efficient approach to cancer therapy.

CPC Classifications

SectionClassGroup
A A61 A61K38/2013
A A61 A61K31/337
A A61 A61K31/444
A A61 A61K31/4439
A A61 A61K31/47
A A61 A61K31/4709
A A61 A61K31/502
A A61 A61K31/506
A A61 A61K31/5025
A A61 A61K31/519
A A61 A61K31/708
A A61 A61K33/243
A A61 A61K38/1774
A A61 A61K39/3955
A A61 A61K45/06
A A61 A61P35/00

Original Patent Information

Patent NumberUS 11,857,601
TitlePharmaceutical composition for cancer treatment comprising fusion protein including IL-2 protein and CD80 protein and anticancer drug
Assignee(s)GI Innovation, Inc.