Adaptive PTH Compounds for Specialized Environments
Legal Citation
Summary of the Inventive Concept
A novel approach to treating hypoparathyroidism in unique operational environments, such as disaster relief, extreme weather conditions, high-security settings, remote areas, and patients with compromised immune systems, utilizing PTH compounds with low peak-to-trough ratios and specialized administration systems.
Background and Problem Solved
The original patent disclosed PTH compounds with low peak-to-trough ratios for treating hypoparathyroidism. However, these compounds were not specifically designed for use in challenging environments or for patients with unique needs. The present inventive concept addresses this limitation by adapting the PTH compounds and administration systems for these specialized scenarios, ensuring effective treatment and minimizing risks.
Detailed Description of the Inventive Concept
The inventive concept comprises PTH compounds with peak-to-trough ratios of less than 4 within one administration interval at a steady state, tailored for use in various niche environments. For disaster relief, a portable, subcutaneous administration device is used. In extreme weather conditions, a handheld, waterproof injection device is employed. For high-security environments, a biometric authentication system ensures secure administration. In remote areas, a kit with a portable, solar-powered refrigeration unit and satellite communication device enables remote monitoring. For patients with compromised immune systems, a sterilization system minimizes infection risk. These specialized variations of the original PTH compounds and administration systems provide effective treatment while addressing the unique challenges of each environment.
Novelty and Inventive Step
The new claims introduce novel, non-obvious variations of the original PTH compounds and administration systems, tailored for specific, high-need environments. The inventive step lies in the adaptation of the compounds and systems to address the unique challenges of these environments, providing effective treatment and minimizing risks.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include additional specialized administration systems, such as wearable devices for continuous monitoring or implantable devices for prolonged treatment. Variations of the PTH compounds could include different formulations or conjugates tailored for specific environments or patient populations.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the pharmaceutical and medical device industries, particularly in the areas of disaster relief, emergency medical care, high-security environments, and remote healthcare. The target market includes governments, NGOs, and private companies operating in these specialized environments, as well as healthcare providers serving patients with unique needs.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K38/29 |
| A | A61 | A61K9/00 |
| A | A61 | A61K47/34 |
| A | A61 | A61K47/60 |
Original Patent Information
| Patent Number | US 11,857,603 |
|---|---|
| Title | PTH compounds with low peak-to-trough ratios |
| Assignee(s) | ASCENDIS PHARMA BONE DISEASES A/S |