PTH-based Soil Remediation and Monitoring
Legal Citation
Summary of the Inventive Concept
Applying PTH compounds with low peak-to-trough ratios to soil quality monitoring, improvement, and remediation, enabling sustainable agriculture and environmental conservation.
Background and Problem Solved
The original patent focused on treating hypoparathyroidism with PTH compounds. However, these compounds' unique pharmacokinetic profiles can be leveraged in entirely new fields. Soil degradation and pollution are pressing global issues, and current methods for monitoring and remediating soil quality are often ineffective or costly. The new inventive concept addresses these limitations by harnessing the potential of PTH compounds in soil applications.
Detailed Description of the Inventive Concept
The new inventive concept involves administering PTH compounds with peak-to-trough ratios of less than 4 to soil to stimulate plant growth, improve soil health, and detect pollutants. The PTH compounds can be used in various formulations, including compositions for treating contaminated soil, devices for detecting soil pollutants, and systems for monitoring soil quality. These applications capitalize on the compounds' ability to interact with soil components and microorganisms, promoting a more sustainable and efficient approach to soil management.
Novelty and Inventive Step
The new claims introduce a paradigm shift by applying PTH compounds to soil-related applications, departing from the original patent's focus on hypoparathyroidism treatment. The inventive step lies in recognizing the potential of PTH compounds to interact with soil components and microorganisms, enabling novel solutions for soil quality monitoring and improvement.
Alternative Embodiments and Variations
Alternative embodiments may include using different PTH compound formulations, adjusting administration frequencies or dosages, or integrating the PTH compounds with other soil amendments or sensors. Variations could involve applying the technology to different types of soil or crops, or developing new devices or systems for PTH compound administration and monitoring.
Potential Commercial Applications and Market
The PTH-based soil remediation and monitoring technology has vast commercial potential in the agricultural and environmental industries. Target markets include sustainable agriculture, soil conservation, and environmental remediation services. The technology could also be licensed to companies developing innovative soil management solutions.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K38/29 |
| A | A61 | A61K9/00 |
| A | A61 | A61K47/34 |
| A | A61 | A61K47/60 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biotechnology and pharmaceutical sciences, with expertise in peptide compound design, pharmacokinetics, and biological interactions across medical and environmental applications
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in biotechnology or pharmaceutical sciences, understanding peptide compound characteristics, pharmacological interactions, and potential cross-domain applications of biological compounds
Obviousness Rationale
A PHOSITA would recognize that the unique pharmacokinetic properties of PTH compounds with low peak-to-trough ratios suggest broader potential applications beyond medical treatment. The compound's inherent characteristics of controlled release and interaction with biological systems naturally invite exploration of alternative uses in environmental and agricultural contexts. The systematic transfer of a known compound's properties to a new technical domain represents a standard approach of technological innovation and would be considered an obvious extension by a skilled practitioner.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,603 |
|---|---|
| Title | PTH compounds with low peak-to-trough ratios |
| Assignee(s) | ASCENDIS PHARMA BONE DISEASES A/S |