Adaptive Nanovector Platform for Personalized Medicine

Publication ID: 24-11857604_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Adaptive Nanovector Platform for Personalized Medicine,” Published Technical Disclosure No. 24-11857604_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857604_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,604.

Summary of the Inventive Concept

A next-generation nanovector platform that enables targeted delivery of active substances with adaptive surface properties, personalized design, real-time monitoring, and modular assembly, revolutionizing the field of precision medicine.

Background and Problem Solved

The original patent for nanovectors and uses has limitations in terms of delivery efficiency, patient-specific treatment, and real-time monitoring. The new inventive concept addresses these limitations by introducing adaptive surface properties, personalized design, and real-time monitoring capabilities, enabling more effective and targeted treatment.

Detailed Description of the Inventive Concept

The adaptive nanovector platform comprises a plurality of nanovectors with surface properties that respond to environmental cues, optimizing delivery efficiency. The platform includes a method for personalized nanovector design, tailoring the nanovector's surface chemistry to a specific patient's biological profile. Additionally, the platform features a sensor module for real-time monitoring of treatment response, tracking the biodistribution and pharmacokinetics of the active substance. The modular nanovector assembly system allows for separate synthesis of the nanoparticle core and surface functional groups, enabling customizable nanovectors with improved stability and efficacy. Furthermore, the platform can be engineered to deliver CRISPR-Cas9 complexes for precision genome editing.

Novelty and Inventive Step

The new claims introduce adaptive surface properties, personalized design, real-time monitoring, and modular assembly, which are not present in the original patent. These features provide a paradigm shift in the field of nanovectors, enabling more effective and targeted treatment.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include varying the type of active substance delivered, using different environmental cues to trigger adaptive surface properties, or integrating the platform with other diagnostic or therapeutic tools. Variations could also include using different materials or manufacturing processes for the nanovectors.

Potential Commercial Applications and Market

The adaptive nanovector platform has significant commercial potential in the fields of precision medicine, gene editing, and targeted therapy. The platform could be marketed to pharmaceutical companies, research institutions, and hospitals, with potential applications in cancer treatment, genetic disorders, and infectious diseases.

CPC Classifications

SectionClassGroup
A A61 A61K38/31
A A61 A61K9/146
A A61 A61K31/704
A A61 A61K33/243
A A61 A61K33/244
A A61 A61K47/6929
A A61 A61K49/0002
A A61 A61K49/128
A A61 A61K49/1881
A A61 A61P35/00
B B82 B82Y5/00
A A61 A61K9/0019

Original Patent Information

Patent NumberUS 11,857,604
TitleNanovectors and uses
Assignee(s)NH THERAGUIX