Next-Generation Nanovector Systems for Personalized Medicine

Publication ID: 24-11857604_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Generation Nanovector Systems for Personalized Medicine,” Published Technical Disclosure No. 24-11857604_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857604_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,604.

Summary of the Inventive Concept

The next-generation nanovector system enables targeted delivery of multiple active substances, leveraging computational frameworks and personalized nanoparticle libraries to revolutionize disease treatment.

Background and Problem Solved

The original patent disclosed nanovectors for delivering active substances, but was limited to single-substance delivery and lacked personalized targeting capabilities. The new inventive concept addresses these limitations by introducing a modular, computational framework-driven approach to nanovector design, enabling tailored therapy for individual patients.

Detailed Description of the Inventive Concept

The next-generation nanovector system comprises a plurality of polysiloxane-based nanoparticles with distinct surface chemistries, each optimized for a specific active substance. A computational framework predicts optimal nanoparticle-substance combinations, and a method for generating personalized nanovector libraries involves analyzing a patient's genetic profile and identifying target active substances. The system also includes a nanovector-based therapeutic platform with stimuli-responsive elements and modular designs for adaptable therapy.

Novelty and Inventive Step

The new claims introduce a paradigm shift in nanovector technology by enabling multi-substance delivery, personalized targeting, and modular design. The computational framework and nanoparticle library generation method are novel and non-obvious, providing a significant inventive step beyond the original patent.

Alternative Embodiments and Variations

Alternative embodiments could include varying nanoparticle core materials, different targeting moieties, or incorporation of additional stimuli-responsive elements. Variations could also involve adapting the computational framework for different disease types or patient populations.

Potential Commercial Applications and Market

The next-generation nanovector system has significant commercial potential in the personalized medicine market, particularly in the treatment of complex diseases such as cancer and genetic disorders. Target industries include pharmaceutical companies, biotechnology firms, and medical research institutions.

CPC Classifications

SectionClassGroup
A A61 A61K38/31
A A61 A61K9/146
A A61 A61K31/704
A A61 A61K33/243
A A61 A61K33/244
A A61 A61K47/6929
A A61 A61K49/0002
A A61 A61K49/128
A A61 A61K49/1881
A A61 A61P35/00
B B82 B82Y5/00
A A61 A61K9/0019

Original Patent Information

Patent NumberUS 11,857,604
TitleNanovectors and uses
Assignee(s)NH THERAGUIX