Expanding Hemoglobin Conjugates: Novel Applications and Use Cases
Legal Citation
Summary of the Inventive Concept
The present inventive concept leverages the core technology of thiosuccinyl-crosslinked hemoglobin conjugates to address unmet needs in diverse industries, including athletic performance, environmental remediation, cancer diagnostics, agriculture, and industrial wastewater treatment.
Background and Problem Solved
The original patent disclosed thiosuccinyl-crosslinked hemoglobin conjugates for repeated doses or prolonged exposure in pharmaceutical applications. However, the full potential of this technology remains untapped in other fields. The present inventive concept addresses this limitation by exploring new applications and use cases that were not originally considered.
Detailed Description of the Inventive Concept
The newly generated claims introduce novel applications of thiosuccinyl-crosslinked hemoglobin conjugates. For instance, Claim 1 describes a system for improving athletic performance by administering the conjugate to enhance endurance. Claim 2 outlines a method for reducing environmental pollutants by using the conjugates to absorb and break down toxic chemicals. Similarly, Claims 3-5 detail the use of these conjugates in cancer diagnostics, agricultural yield enhancement, and industrial wastewater treatment, respectively. These new applications capitalize on the unique properties of thiosuccinyl-crosslinked hemoglobin conjugates, such as their ability to bind to specific targets and facilitate biochemical reactions.
Novelty and Inventive Step
The novelty of the present inventive concept lies in the unexpected application of thiosuccinyl-crosslinked hemoglobin conjugates to unrelated fields, thereby creating new opportunities for innovation and problem-solving. The inventive step resides in the identification of these new use cases and the development of corresponding systems and methods.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of different polymer types, linker chemistries, or crosslinking moieties to tailor the conjugates for specific applications. Additionally, the conjugates could be modified to target specific cell types or tissues, further expanding their potential uses.
Potential Commercial Applications and Market
The present inventive concept has significant commercial potential across multiple industries, including sports medicine, environmental remediation, cancer diagnostics, agriculture, and industrial wastewater treatment. The market size for these applications is substantial, and the inventive concept offers a unique value proposition by leveraging the established technology of thiosuccinyl-crosslinked hemoglobin conjugates.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K38/42 |
| A | A61 | A61K47/542 |
| A | A61 | A61K47/545 |
| A | A61 | A61K47/60 |
| A | A61 | A61P9/10 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biomedical engineering and pharmaceutical chemistry, specifically protein conjugation technologies, polymer chemistry, and biomolecular modification techniques. Expertise requires advanced degrees in chemistry, biochemistry, or bioengineering with specialized knowledge of protein modification strategies and polymer conjugation methods
Person of Ordinary Skill (PHOSITA) Profile
A skilled practitioner with advanced training in protein engineering, capable of understanding complex molecular modification techniques, familiar with polyethylene glycol conjugation strategies, and experienced in designing functional biomolecular systems with enhanced properties
Obviousness Rationale
The published technical disclosure represents predictable extensions of the source patent's core technology by applying known thiosuccinyl-crosslinked hemoglobin conjugate principles to novel application domains. A person having ordinary skill would recognize that the fundamental molecular engineering approach disclosed in US 11857605 could be readily adapted to diverse fields by leveraging the conjugate's inherent binding and transport capabilities. The variations represent systematic exploration of a well-characterized molecular platform using standard biotechnological design principles.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,605 |
|---|---|
| Title | Thiosuccinyl-crosslinked hemoglobin conjugates and methods of use and preparation thereof |
| Assignee(s) | Billion King International Limited |