Novel Applications of Thiosuccinyl-Crosslinked Hemoglobin Conjugates
Legal Citation
Summary of the Inventive Concept
This inventive concept leverages the core technology of thiosuccinyl-crosslinked hemoglobin conjugates to address various unmet needs in industries beyond pharmaceuticals, including agricultural pest control, bioremediation, cosmetics, environmental monitoring, and food processing.
Background and Problem Solved
The original patent disclosed thiosuccinyl-crosslinked hemoglobin conjugates for pharmaceutical applications, but their potential extends far beyond. This inventive concept addresses the limitations of existing solutions in other industries, where the conjugates' unique properties can provide significant benefits.
Detailed Description of the Inventive Concept
The new claims describe systems and methods that utilize thiosuccinyl-crosslinked hemoglobin conjugates in novel applications. For example, in agricultural pest control, the conjugate can deliver pesticides to targeted areas, reducing environmental impact. In bioremediation, the conjugate can bind to heavy metals, facilitating their removal from contaminated sites. Similarly, the conjugate can be used in cosmetics to deliver active ingredients to the skin, in environmental monitoring to detect pollutants, and in food processing to extend product shelf life.
Novelty and Inventive Step
The new claims introduce a paradigm shift in the application of thiosuccinyl-crosslinked hemoglobin conjugates, moving beyond pharmaceuticals to address unmet needs in various industries. This inventive concept is non-obvious because it requires a deep understanding of the conjugates' properties and their potential to solve real-world problems in diverse fields.
Alternative Embodiments and Variations
Other embodiments of this inventive concept could include using different types of polymers or linkers, varying the molecular weight of the conjugate, or exploring alternative methods of administration or detection. These variations could further expand the conjugates' potential in various industries.
Potential Commercial Applications and Market
This inventive concept has significant commercial potential, as it addresses pressing needs in multiple industries. The market for these applications is substantial, with potential customers including agricultural companies, bioremediation service providers, cosmetics manufacturers, environmental monitoring agencies, and food processing companies.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K38/42 |
| A | A61 | A61K47/542 |
| A | A61 | A61K47/545 |
| A | A61 | A61K47/60 |
| A | A61 | A61P9/10 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biomedical engineering and polymer chemistry, specifically protein conjugation techniques involving hemoglobin modification, drug delivery systems, and biomolecular engineering with a focus on polyethylene glycol (PEG) conjugation strategies
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in bioengineering or chemical engineering, possessing expertise in protein modification, polymer chemistry, and interdisciplinary applications of biomolecular conjugates, with knowledge of crosslinking techniques and polymer-protein interactions
Obviousness Rationale
A person having ordinary skill would recognize that the thiosuccinyl-crosslinked hemoglobin conjugates disclosed in the source patent inherently possess versatile properties that enable broad application across multiple technical domains. The fundamental molecular structure and crosslinking mechanism described in the source patent provide a predictable platform for extending the conjugate's utility beyond pharmaceutical applications. The PTD's proposed variations represent logical extensions of the core technological concept by leveraging the conjugate's inherent binding and delivery capabilities.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,605 |
|---|---|
| Title | Thiosuccinyl-crosslinked hemoglobin conjugates and methods of use and preparation thereof |
| Assignee(s) | Billion King International Limited |