Tissue Kallikrein 1-Based Formulations for Agricultural and Environmental Applications

Publication ID: 24-11857608_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Tissue Kallikrein 1-Based Formulations for Agricultural and Environmental Applications,” Published Technical Disclosure No. 24-11857608_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857608_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,608.

Summary of the Inventive Concept

This inventive concept leverages the core technology of tissue kallikrein 1 (KLK1) polypeptides to develop innovative solutions for agricultural and environmental challenges, including crop growth enhancement, soil erosion prevention, wildfire prevention, and water quality improvement.

Background and Problem Solved

The original patent disclosed dosage forms of tissue kallikrein 1 for treating ischemic conditions. However, the limitations of this technology in addressing agricultural and environmental issues prompted the development of new applications and use cases. The inventive concept addresses the need for sustainable and effective solutions in these fields.

Detailed Description of the Inventive Concept

The new claims describe systems, methods, and compositions that utilize KLK1-based formulations to enhance plant growth and stress resistance, reduce soil erosion, predict and prevent wildfires, and improve water quality. These formulations can be administered through various means, including subcutaneous or intravenous injection, and can be monitored using sensor systems. The KLK1 polypeptides interact with plant cells to stimulate growth and increase resistance to environmental stressors, while also reducing vegetation water content to prevent wildfires.

Novelty and Inventive Step

The new claims introduce a paradigm shift in the application of KLK1 technology, moving from ischemic condition treatment to agricultural and environmental solutions. The inventive step lies in the recognition of KLK1's potential in these new fields and the development of formulations and systems that effectively address specific challenges.

Alternative Embodiments and Variations

Alternative embodiments may include different KLK1 polypeptide formulations, varying administration methods, and diverse sensor systems for monitoring crop growth and stress levels. Variations may also involve integrating KLK1 technology with existing agricultural and environmental practices to create hybrid solutions.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the agricultural and environmental industries, with potential applications in crop enhancement, soil conservation, wildfire prevention, and water quality management. The target market includes agricultural companies, environmental organizations, and government agencies seeking sustainable and effective solutions to pressing challenges.

CPC Classifications

SectionClassGroup
A A61 A61K38/4853
A A61 A61K9/0019
A A61 A61K45/06
C C12 C12Y304/21035

Original Patent Information

Patent NumberUS 11,857,608
TitleDosage forms of tissue kallikrein 1
Assignee(s)DiaMedica Inc.