Next-Generation Necrotic Enteritis Vaccine System
Legal Citation
Summary of the Inventive Concept
A pioneering vaccine system for necrotic enteritis in poultry, leveraging plant-based expression, nanocapsule delivery, and AI-driven development to provide unparalleled protection against C. perfringens infection.
Background and Problem Solved
The original patent's vaccine composition, while effective, has limitations in terms of production scalability, delivery efficiency, and adaptability to emerging strains. This new inventive concept addresses these limitations by introducing a novel, plant-based expression system for producing fusion proteins, a slow-release nanocapsule delivery system, and AI-driven development to accelerate vaccine development and enhance efficacy.
Detailed Description of the Inventive Concept
The new inventive concept comprises a plant-based expression system engineered to produce a PlcC-NetB fusion protein, which is then administered to poultry in a slow-release, nanocapsule-based delivery system. This system enables prolonged protection against C. perfringens infection. Additionally, the inventive concept incorporates an AI-driven development platform to identify optimal antigen combinations and adjuvants, thereby accelerating the development of effective vaccines. The system also includes a wearable device for monitoring the bird's health status, coupled with a machine learning algorithm to predict the likelihood of C. perfringens infection, enabling early intervention and prevention.
Novelty and Inventive Step
The new claims introduce a paradigm shift in necrotic enteritis vaccine development by integrating plant-based expression, nanocapsule delivery, and AI-driven development. These novel elements provide a significant improvement over the original patent's composition, offering enhanced efficacy, scalability, and adaptability.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include using different plant-based expression systems, varying the composition of the nanocapsule delivery system, or incorporating additional AI-driven tools for vaccine development and monitoring. These variations would ensure broad conceptual coverage and adaptability to diverse poultry production settings.
Potential Commercial Applications and Market
The next-generation necrotic enteritis vaccine system has significant commercial potential in the poultry industry, with potential applications in vaccine development, production, and distribution. The target market includes poultry farmers, vaccine manufacturers, and animal health companies seeking to improve bird health and reduce mortality rates.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K39/08 |
| A | A61 | A61P31/04 |
| C | C12 | C12N15/74 |
| C | C12 | C12N15/8258 |
| A | A61 | A61K2039/552 |
| A | A61 | A61K2039/55577 |
Original Patent Information
| Patent Number | US 11,857,613 |
|---|---|
| Title | Vaccine for prevention of necrotic enteritis in poultry |
| Assignee(s) | Arizona Board of Regents on Behalf of Arizona State University |