Synergistic Vaccine System for Necrotic Enteritis Prevention in Poultry

Publication ID: 24-11857613_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Vaccine System for Necrotic Enteritis Prevention in Poultry,” Published Technical Disclosure No. 24-11857613_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857613_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,613.

Summary of the Inventive Concept

A comprehensive system integrating a novel vaccine, blockchain, IoT, AI, and plant-based delivery to prevent necrotic enteritis in poultry, providing real-time monitoring, data-driven decision making, and optimized vaccine distribution.

Background and Problem Solved

The original patent addressed the limitations of existing vaccines for necrotic enteritis in poultry, but lacked a comprehensive system for prevention and control. This new inventive concept integrates distinct technologies to create a powerful system that overcomes the limitations of the original patent.

Detailed Description of the Inventive Concept

The system comprises a blockchain-based vaccine tracking module, a cloud-based data analytics platform, and a machine learning algorithm for predicting disease outbreaks. The vaccine is administered orally through a plant-based delivery system comprising a fusion protein combining immunogenic and non-toxic components of alpha-toxin and NetB. IoT sensors track environmental conditions, and AI-powered image recognition detects disease symptoms. The vaccine is delivered through a drone-based system, and the blockchain-based supply chain management system optimizes vaccine distribution.

Novelty and Inventive Step

The new claims introduce a synergistic combination of technologies, including blockchain, IoT, AI, and plant-based delivery, which are not present in the original patent. The inventive step lies in the integration of these technologies to create a comprehensive system for necrotic enteritis prevention and control.

Alternative Embodiments and Variations

Alternative embodiments may include using different types of sensors, machine learning algorithms, or blockchain platforms. Variations may include adapting the system for use in different poultry production settings or integrating additional technologies, such as robotics or nanotechnology.

Potential Commercial Applications and Market

The synergistic vaccine system has significant commercial potential in the poultry industry, with potential applications in disease prevention and control, supply chain management, and data-driven decision making. The target market includes poultry producers, veterinarians, and animal health companies.

CPC Classifications

SectionClassGroup
A A61 A61K39/08
A A61 A61P31/04
C C12 C12N15/74
C C12 C12N15/8258
A A61 A61K2039/552
A A61 A61K2039/55577

Original Patent Information

Patent NumberUS 11,857,613
TitleVaccine for prevention of necrotic enteritis in poultry
Assignee(s)Arizona Board of Regents on Behalf of Arizona State University