Published Technical Disclosure Archive

Vaccine Systems for Specialized Poultry Environments

Publication ID: 24-11857613_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Vaccine Systems for Specialized Poultry Environments,” Published Technical Disclosure No. 24-11857613_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857613_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,613.

Summary of the Inventive Concept

The inventive concept discloses specialized vaccine systems for protecting poultry from necrotic enteritis in unique operational environments, including high-security farms, extreme weather conditions, disaster relief situations, and free-range poultry settings.

Background and Problem Solved

The original patent disclosed a vaccine for preventing necrotic enteritis in poultry, but it lacked adaptability for specific, narrow market or unique operational environments. The new inventive concept addresses this limitation by providing specialized vaccine systems that cater to these niche markets, ensuring effective protection of poultry in diverse settings.

Detailed Description of the Inventive Concept

The inventive concept comprises a range of vaccine systems, including oral vaccines for high-security farms, temperature-resistant vaccines for extreme weather conditions, emergency kits for disaster relief situations, and wireless tracking systems for free-range poultry. These systems incorporate the PlcC-NetB fusion protein vaccine, which has been optimized for each specific environment. The vaccine composition, delivery device, and instructions for administration have been tailored to meet the unique demands of each niche market.

Novelty and Inventive Step

The new claims introduce novel and non-obvious features, including the adaptation of the PlcC-NetB fusion protein vaccine for high-security farms, extreme weather conditions, disaster relief situations, and free-range poultry settings. The inventive concept's specialized vaccine systems and components provide a unique solution for protecting poultry in these unique operational environments.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include, but are not limited to, aerosol-based vaccines for high-security farms, vaccine compositions with enhanced stability for extreme weather conditions, and wearable devices for tracking poultry health in free-range settings.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the poultry industry, particularly in niche markets such as high-security farms, disaster relief operations, and free-range poultry production. The specialized vaccine systems can provide a competitive edge in these markets, ensuring the health and well-being of poultry in diverse operational environments.

CPC Classifications

SectionClassGroup
A A61 A61K39/08
A A61 A61P31/04
C C12 C12N15/74
C C12 C12N15/8258
A A61 A61K2039/552
A A61 A61K2039/55577

Field of Art

Veterinary immunology and vaccine development, specifically focused on poultry disease prevention, with expertise in protein engineering, microbiology, and vaccine formulation technologies

Person of Ordinary Skill (PHOSITA) Profile

A researcher with advanced degrees in veterinary science or microbiology, experienced in protein fusion techniques, vaccine design, and understanding of bacterial pathogen interactions in poultry environments

Obviousness Rationale

A PHOSITA would recognize that the source patent's PlcC-NetB fusion protein provides a foundational vaccine technology that can be readily adapted to various environmental and operational contexts. The technical variations in the PTD represent predictable extensions of the core vaccine concept, utilizing standard vaccine development techniques such as formulation modification, delivery system optimization, and targeted application strategies. These variations demonstrate routine problem-solving within the field of veterinary vaccine design.

Obvious Combinations & Variations

Source Patent Element
PlcC-NetB fusion protein for preventing C. perfringens infection in poultry
PTD Variation
Specialized vaccine delivery systems for high-security farms, extreme weather conditions, and disaster relief scenarios
Obviousness Reasoning
A PHOSITA would recognize that adapting vaccine delivery to specific environmental conditions represents a standard design optimization process, involving predictable modifications to formulation, packaging, and administration methods
Source Patent Element
Protein sequence with specific amino acid substitutions (Y191A, R200A, W257A)
PTD Variation
Incorporation of wireless tracking and remote monitoring systems for vaccine administration and disease detection
Obviousness Reasoning
Integrating tracking technologies with vaccine delivery is a predictable technological advancement that combines known techniques in veterinary health monitoring with existing vaccine platforms
Source Patent Element
Base vaccine composition targeting C. perfringens
PTD Variation
Development of oral vaccine supplements and emergency immunization kits
Obviousness Reasoning
Modifying vaccine administration routes and creating emergency preparedness solutions represent standard problem-solving techniques within veterinary vaccine development, utilizing known formulation and delivery strategies
Source Patent Element
Protein fusion technique combining PlcC and NetB protein units
PTD Variation
Adding adjuvants and preservatives to enhance vaccine stability and long-term storage capabilities
Obviousness Reasoning
Enhancing vaccine stability through standard formulation techniques is a predictable extension of existing vaccine development practices, representing routine optimization within the field
Source Patent Element
Base vaccine targeting necrotic enteritis in poultry
PTD Variation
Specialized vaccines for free-range poultry environments with unique disease transmission risks
Obviousness Reasoning
Tailoring vaccine strategies to specific poultry production environments represents a standard approach to addressing varied agricultural contexts, utilizing known protein engineering and vaccine design principles
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the variations disclosed in the instant publication would have been obvious to a person having ordinary skill in the art at the time of invention, as they represent predictable extensions of the foundational vaccine technology disclosed in US Patent 11857613, utilizing standard techniques in protein engineering, vaccine formulation, and veterinary immunology to address specific environmental and operational challenges in poultry disease prevention.

Original Patent Information

Patent NumberUS 11,857,613
TitleVaccine for prevention of necrotic enteritis in poultry
Assignee(s)Arizona Board of Regents on Behalf of Arizona State University