Flagellin Polypeptides for Diverse Applications

Publication ID: 24-11857614_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Flagellin Polypeptides for Diverse Applications,” Published Technical Disclosure No. 24-11857614_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857614_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,614.

Summary of the Inventive Concept

This inventive concept explores the application of Enterococcus gallinarum flagellin polypeptides in novel industries and use cases, leveraging their immunomodulatory properties to stimulate defense responses and improve outcomes in agriculture, bioremediation, cosmetics, veterinary care, and biodegradable packaging.

Background and Problem Solved

The original patent focused on pharmaceutical compositions for treating diseases. However, the immunomodulatory properties of Enterococcus gallinarum flagellin polypeptides have broader potential. This inventive concept addresses the limitation of the original patent by exploring new applications and use cases, solving the problem of underutilization of these polypeptides.

Detailed Description of the Inventive Concept

The new claims introduce novel applications of Enterococcus gallinarum flagellin polypeptides. For instance, in agriculture, these polypeptides can be used to stimulate plant defense responses, increasing crop yields and resistance to pathogens. In bioremediation, they can enhance microbial activity, promoting the degradation of pollutants in contaminated soil. In cosmetics, they can stimulate skin defense responses, improving skin health. In veterinary care, they can stimulate immune responses, preventing disease in animals. Finally, in biodegradable packaging, they can inhibit microbial growth, extending the shelf life of packaged products.

Novelty and Inventive Step

The new claims introduce a paradigm shift in the application of Enterococcus gallinarum flagellin polypeptides, moving from pharmaceutical compositions to diverse industries and use cases. This inventive concept is novel and non-obvious, as it requires a deep understanding of the polypeptides' immunomodulatory properties and their potential in new applications.

Alternative Embodiments and Variations

Alternative embodiments of this inventive concept could include using different bacterial strains or modifying the flagellin polypeptides to enhance their efficacy. Variations could also include combining these polypeptides with other compounds or technologies to create synergistic effects.

Potential Commercial Applications and Market

This inventive concept has significant commercial potential, as it addresses pressing needs in various industries. The market for these applications is substantial, with potential customers including agricultural companies, bioremediation service providers, cosmetic manufacturers, veterinary care providers, and biodegradable packaging companies.

CPC Classifications

SectionClassGroup
A A61 A61K39/09
A A61 A61K35/744
A A61 A61K2039/585
A A61 A61P37/04

Original Patent Information

Patent NumberUS 11,857,614
TitleEnterococcus gallinarum flagellin polypeptides
Assignee(s)CJ BIOSCIENCE, INC.