Flagellin Polypeptide-Based Water Quality Monitoring and Remediation Systems

A novel application of Enterococcus gallinarum flagellin polypeptides in water quality monitoring and remediation systems, enabling real-time detection and mitigation of waterborne pathogens and algae growth.

The original patent disclosed the use of Enterococcus gallinarum flagellin polypeptides in pharmaceutical compositions for treating diseases. However, the patent did not consider the potential of these polypeptides in addressing water quality issues. The new inventive concept solves the problem of inadequate water quality monitoring and remediation by leveraging the flagellin polypeptides' ability to interact with waterborne pathogens and algae.

The new inventive concept encompasses systems, methods, and devices that utilize isolated Enterococcus gallinarum flagellin polypeptides to monitor and mitigate water pollution. These systems comprise sensors for detecting interactions between the flagellin polypeptides and waterborne pathogens or algae, triggering alarms or remediation responses. The methods involve administering the flagellin polypeptides to water samples, detecting interactions, and tracing the source of waterborne outbreaks. Devices can be designed to remove waterborne pathogens from water supplies or control algae growth in aquatic ecosystems.

The new claims introduce a previously unknown application of Enterococcus gallinarum flagellin polypeptides in water quality monitoring and remediation, which is not obvious from the original patent's disclosure of pharmaceutical compositions. The inventive step lies in recognizing the potential of these polypeptides in interacting with waterborne pathogens and algae, and designing systems, methods, and devices that harness this property for water quality management.

Alternative embodiments could include using different bacterial strains or polypeptide sequences, integrating the flagellin polypeptides with existing water treatment infrastructure, or developing portable or point-of-use devices for water quality monitoring and remediation.

The inventive concept has significant commercial potential in the water quality monitoring and remediation market, which is projected to grow substantially in the coming years. Target industries include municipal water treatment, industrial process water management, and environmental monitoring and remediation services.