Adaptive Flagellin Polypeptide Solutions for Niche Environments
Legal Citation
Summary of the Inventive Concept
The inventive concept adapts Enterococcus gallinarum flagellin polypeptides for specialized applications in high-security, disaster relief, extreme weather, and remote areas, enhancing immune response and disease treatment in these unique operational environments.
Background and Problem Solved
The original patent disclosed pharmaceutical compositions comprising Enterococcus flagellin polypeptides for general disease treatment. However, these compositions were not tailored for specific, high-stakes environments. This inventive concept addresses the limitations of the original patent by developing specialized solutions for niche markets, ensuring effective disease treatment and immune response in challenging conditions.
Detailed Description of the Inventive Concept
The inventive concept encompasses four primary variations: 1) a system for treating infectious diseases in remote or disaster-stricken areas, featuring a portable storage unit and disposable delivery device; 2) a method for enhancing immune response in individuals exposed to extreme weather conditions, utilizing a cryoprotectant; 3) a kit for high-security biodefense applications, incorporating a decontamination agent and portable diagnostic device; and 4) a composition for treating diseases in high-altitude or extreme-temperature environments, employing a thermally stabilized excipient. These adaptations ensure the effective use of Enterococcus gallinarum flagellin polypeptides in these unique environments.
Novelty and Inventive Step
The new claims introduce novel, non-obvious adaptations of the original Enterococcus gallinarum flagellin polypeptide compositions, specifically designed for high-security, disaster relief, extreme weather, and remote areas. These specialized solutions overcome the limitations of the original patent, providing a new level of effectiveness and reliability in these niche environments.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include integrating the flagellin polypeptide compositions with wearable devices, autonomous diagnostic systems, or advanced cryopreservation techniques to further enhance their utility in specialized applications.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the biodefense, disaster relief, and extreme environment industries, offering tailored solutions for high-stakes, niche markets. Potential applications include rapid disease diagnosis and treatment in emergency response situations, as well as enhanced immune response in individuals operating in extreme weather conditions.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K39/09 |
| A | A61 | A61K35/744 |
| A | A61 | A61K2039/585 |
| A | A61 | A61P37/04 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Immunology, microbiology, and pharmaceutical compositions, specifically focusing on bacterial flagellin polypeptides and their therapeutic applications. Requires expertise in protein engineering, immunological response mechanisms, and pharmaceutical formulation techniques
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in microbiology or immunology, experienced in protein characterization, drug delivery systems, and understanding bacterial protein interactions with immune systems. Familiar with techniques for modifying protein compositions for specialized environmental conditions
Obviousness Rationale
A person having ordinary skill would recognize that the source patent's Enterococcus gallinarum flagellin polypeptide provides a foundational composition that can be readily adapted for specialized environments using standard pharmaceutical engineering techniques. The PTD's variations represent predictable extensions of the original patent's core immunological technology, applying known formulation strategies to enhance utility in challenging operational contexts. These adaptations would be considered routine optimization within the skilled artisan's capabilities.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,614 |
|---|---|
| Title | Enterococcus gallinarum flagellin polypeptides |
| Assignee(s) | CJ BIOSCIENCE, INC. |