Novel Applications of Acinetobacter baumannii-Derived Peptides in Environmental Monitoring and Bioremediation
Legal Citation
Summary of the Inventive Concept
The present inventive concept leverages the core technology of peptides derived from Acinetobacter baumannii to address pressing environmental and industrial challenges, including pollution monitoring, bioremediation, and food safety.
Background and Problem Solved
The original patent focused on the antimicrobial prophylaxis and therapy applications of Acinetobacter baumannii-derived peptides. However, the peptides' unique properties also make them suitable for detecting and responding to environmental pollutants, industrial waste, and foodborne pathogens. The present inventive concept addresses the limitations of existing methods in these areas, which often rely on costly, time-consuming, and insensitive detection techniques.
Detailed Description of the Inventive Concept
The new inventive concept involves the use of Acinetobacter baumannii-derived peptides as biosensors, diagnostic tools, and bioremediation agents. Specifically, the peptides can be engineered to detect heavy metal ions, pesticides, and foodborne pathogens with high sensitivity and specificity. The peptides can be immobilized on solid supports, conjugated to fluorescent labels, or expressed in microorganisms to create versatile detection systems. Additionally, the peptides can be used to degrade industrial waste and detect bioterrorism agents.
Novelty and Inventive Step
The new claims introduce novel applications of Acinetobacter baumannii-derived peptides, which are not obvious from the original patent. The inventive step lies in recognizing the peptides' potential in environmental monitoring and bioremediation, and developing specific systems and methods to harness this potential.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of different peptide sequences, detection formats, or expression systems. For example, the peptides could be used in electrochemical biosensors, or expressed in plant-based systems for bioremediation. Variations could also include the development of peptide-based diagnostic kits for detecting other types of pollutants or pathogens.
Potential Commercial Applications and Market
The present inventive concept has significant commercial potential in the environmental monitoring, bioremediation, and food safety industries. The development of peptide-based biosensors and diagnostic tools could provide cost-effective and efficient solutions for detecting pollutants and pathogens, while the bioremediation applications could offer a sustainable approach to waste management. The target market includes government agencies, environmental consulting firms, and companies involved in food production and processing.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K39/104 |
| C | C07 | C07K14/212 |
| A | A61 | A61K2039/543 |
| A | A61 | A61K2039/55505 |
| A | A61 | A61K2039/55566 |
| G | G01 | G01N2333/22 |
| G | G01 | G01N2469/20 |
Original Patent Information
| Patent Number | US 11,857,615 |
|---|---|
| Title | Peptides derived from Acinetobacter baumannii and their use in vaccination |
| Assignee(s) | Evaxion Biotech A/S |