Specialized Peptide-based Vaccination Solutions for Niche Environments

Publication ID: 24-11857615_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Peptide-based Vaccination Solutions for Niche Environments,” Published Technical Disclosure No. 24-11857615_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857615_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,615.

Summary of the Inventive Concept

This inventive concept adapts peptide-based vaccination technology for specific, high-need environments, including disaster relief, high-security facilities, extreme weather conditions, high-altitude environments, and remote areas.

Background and Problem Solved

The original patent disclosed peptide-based vaccination technology for antimicrobial prophylaxis and therapy. However, it did not address the unique challenges and requirements of vaccination in specialized environments. This inventive concept addresses these limitations by providing tailored solutions for niche markets.

Detailed Description of the Inventive Concept

The inventive concept comprises four specialized variations of the original peptide-based vaccination technology. Firstly, a method for disaster relief vaccination involves administering the pharmaceutical composition in a post-disaster setting to immunize against Acinetobacter baumannii infections. Secondly, a system for high-security vaccination features a secure storage unit for storing the composition in a high-security facility. Thirdly, a pharmaceutical composition for extreme weather vaccination is formulated to withstand extreme temperatures. Lastly, methods for vaccination in high-altitude environments and remote areas involve formulating the composition to withstand low oxygen levels and using portable storage units, respectively.

Novelty and Inventive Step

The new claims introduce novel and non-obvious adaptations of the original peptide-based vaccination technology for specific, high-need environments. These adaptations involve unique formulations, storage solutions, and administration methods tailored to the requirements of each environment.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include adaptations for other niche environments, such as space exploration, military operations, or emergency response situations. Variations could also involve different peptide sequences, adjuvants, or carriers tailored to specific environments or applications.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the vaccination market, particularly in niche areas such as disaster relief, high-security facilities, extreme weather conditions, high-altitude environments, and remote areas. Target industries could include government agencies, private security companies, and humanitarian organizations.

CPC Classifications

SectionClassGroup
A A61 A61K39/104
C C07 C07K14/212
A A61 A61K2039/543
A A61 A61K2039/55505
A A61 A61K2039/55566
G G01 G01N2333/22
G G01 G01N2469/20

Field of Art

Biotechnology and pharmaceutical vaccine development, specifically focused on peptide-based immunological compositions for infectious disease prevention, with expertise in microbial protein engineering, vaccine formulation, and specialized delivery systems

Person of Ordinary Skill (PHOSITA) Profile

A skilled researcher with advanced degrees in microbiology or biotechnology, experienced in vaccine design, protein modification, and understanding environmental adaptation strategies for pharmaceutical compositions

Obviousness Rationale

A person having ordinary skill would recognize that adapting the Acinetobacter baumannii peptide vaccine to specialized environments represents predictable variations within standard vaccine development practices. The core peptide composition remains substantially unchanged, with modifications focusing on delivery, storage, and environmental resilience. These adaptations represent routine engineering solutions that would be apparent to a skilled practitioner seeking to expand vaccine utility across challenging contexts.

Obvious Combinations & Variations

Source Patent Element
Polypeptide composition derived from Acinetobacter baumannii with specific amino acid sequence variations
PTD Variation
Disaster relief vaccination method using identical peptide composition in post-disaster settings
Obviousness Reasoning
Extending vaccine application to emergency contexts represents a predictable design choice addressing known infectious disease transmission risks in humanitarian scenarios
Source Patent Element
Pharmaceutical composition with aluminum-based adjuvant
PTD Variation
Extreme temperature-resistant formulation maintaining vaccine stability
Obviousness Reasoning
Modifying vaccine carrier to enhance environmental stability is a standard engineering approach using known stabilization techniques in pharmaceutical development
Source Patent Element
Polypeptide with 30-509 contiguous amino acid residues
PTD Variation
High-altitude and remote area vaccination methods with specialized storage solutions
Obviousness Reasoning
Adapting vaccine delivery mechanisms for challenging environments represents a logical extension of standard vaccine development practices, utilizing known protein engineering and formulation strategies
Source Patent Element
Immunological composition with specific sequence identity requirements
PTD Variation
High-security storage system with controlled access and preservation protocols
Obviousness Reasoning
Implementing specialized storage solutions for sensitive biological materials is a predictable technical solution within vaccine development and biosecurity domains
Source Patent Element
Peptide-based vaccination methodology
PTD Variation
Portable kit design for vaccination in remote environments
Obviousness Reasoning
Creating transportable vaccine delivery systems represents a routine engineering adaptation addressing known logistical challenges in medical interventions
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857615 and the published technical disclosure, a person having ordinary skill in the art would find the claimed variations obvious and anticipated, as the disclosed adaptations represent predictable extensions of existing peptide-based vaccination technologies through routine engineering modifications that do not introduce non-obvious technical innovations.

Original Patent Information

Patent NumberUS 11,857,615
TitlePeptides derived from Acinetobacter baumannii and their use in vaccination
Assignee(s)Evaxion Biotech A/S