Environmental Monitoring and Food Safety Systems using Recombinant Measles Virus

Publication ID: 24-11857616_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Environmental Monitoring and Food Safety Systems using Recombinant Measles Virus,” Published Technical Disclosure No. 24-11857616_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857616_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,616.

Summary of the Inventive Concept

A novel application of recombinant measles virus technology for detecting pollutants in various industries, including environmental monitoring, food safety, and construction materials.

Background and Problem Solved

The original patent disclosed a recombinant measles virus expressing Zika virus proteins for vaccine development. However, the detection of pollutants in various industries remains a significant challenge. The new inventive concept addresses this limitation by leveraging the core technology to develop systems for monitoring environmental pollutants, detecting contaminants in food and agricultural products, and analyzing construction materials.

Detailed Description of the Inventive Concept

The new inventive concept involves the design and development of recombinant measles viruses expressing modified Zika virus proteins capable of detecting pollutants in different industries. The modified proteins can be engineered to bind specifically to pollutants, allowing for their detection and quantification. The recombinant measles viruses can be used in various systems, including environmental monitoring systems, food safety testing devices, and construction material analysis tools. The viruses can be engineered to express different proteins, each tailored to detect specific pollutants or contaminants, thereby expanding the range of applications.

Novelty and Inventive Step

The new claims introduce a novel application of recombinant measles virus technology, shifting from vaccine development to pollutant detection in various industries. The inventive step lies in the recognition of the potential of the core technology to be adapted for environmental monitoring, food safety, and construction material analysis, and the development of modified Zika virus proteins for pollutant detection.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different viral vectors, such as adenovirus or lentivirus, to express the modified Zika virus proteins. Additionally, the system could be designed to detect multiple pollutants simultaneously, or to integrate with existing monitoring systems.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including environmental monitoring, food safety, and construction materials. The market for pollutant detection and monitoring is substantial, with an estimated value of over $10 billion annually. The technology could be licensed to companies operating in these industries, or developed into products and services offered by the patent holder.

CPC Classifications

SectionClassGroup
A A61 A61K39/12
C C07 C07K14/005
C C12 C12N7/00
A A61 A61K2039/5254
A A61 A61K2039/53
C C12 C12N2760/18421
C C12 C12N2760/18423
C C12 C12N2770/24122
C C12 C12N2770/24123
C C12 C12N2770/24134

Original Patent Information

Patent NumberUS 11,857,616
TitleRecombinant measles virus expressing zika virus prM and E proteins
Assignee(s)CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Institut Pasteur