Applying Combination Treatment to Novel Industries

Publication ID: 24-11857617_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Applying Combination Treatment to Novel Industries,” Published Technical Disclosure No. 24-11857617_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857617_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,617.

Summary of the Inventive Concept

The inventive concept extends the core technology of the original patent to new applications and use cases, focusing on agricultural practices, bee protection, food safety, zoonotic disease prevention, and crop disease mitigation.

Background and Problem Solved

The original patent addressed the treatment and prevention of infections using drug and vaccination combination treatment. However, the patent's scope was limited to human infections. This inventive concept tackles the limitations by applying the core technology to novel industries, solving problems such as environmental degradation, colony collapse disorder, foodborne illnesses, and crop diseases.

Detailed Description of the Inventive Concept

The inventive concept comprises a combination of a pesticide and a plant vaccine directed to a causative agent of plant infections, protecting bees from colony collapse disorder using an anti-microbial drug combination and a vaccine, improving food safety through a combination of an anti-microbial drug and a vaccine, preventing the spread of zoonotic diseases by administering an anti-microbial drug combination and a vaccine to animals, and reducing the economic impact of crop diseases using a combination of a pesticide and a plant vaccine. Each application leverages the synergistic effects of the drug and vaccine combination, providing a novel solution to the respective industry's problems.

Novelty and Inventive Step

The inventive concept's novelty lies in its application of the original patent's core technology to entirely new industries, addressing previously unconsidered problems. The inventive step resides in the adaptation of the combination treatment to novel contexts, requiring a deep understanding of the specific challenges and requirements of each industry.

Alternative Embodiments and Variations

Alternative embodiments may include varying the type and dosage of the pesticide, anti-microbial drug, or vaccine used in each application. Variations could also involve adjusting the administration schedule, route of administration, or formulation of the combination treatment. Additionally, the inventive concept could be expanded to other industries, such as aquaculture or veterinary medicine, to address similar problems.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the agricultural, beekeeping, food safety, animal health, and crop protection industries. The market for these applications is substantial, with the global agricultural industry alone projected to reach USD 5.5 trillion by 2025. The inventive concept's ability to address pressing problems in these industries positions it for widespread adoption and significant revenue generation.

CPC Classifications

SectionClassGroup
A A61 A61K39/12
A A61 A61K31/166
A A61 A61K45/06
A A61 A61P31/14
C C12 C12N7/00
A A61 A61K2039/545

Field of Art

Medical and veterinary biotechnology, focusing on combination treatments for infectious diseases across biological systems, with expertise in pharmacology, immunology, and drug delivery mechanisms

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in biotechnology, microbiology, or pharmaceutical sciences, possessing knowledge of drug combination strategies, vaccine development, and cross-domain disease prevention techniques

Obviousness Rationale

A PHOSITA would recognize the fundamental principle of combination treatment from the source patent and understand its potential for broad application across different biological systems. The core concept of using simultaneous drug and vaccine interventions is directly transferable to agricultural, zoonotic, and food safety contexts. The technical framework established in the original patent provides a clear template for extending the treatment methodology to novel domains with predictable and reproducible results.

Obvious Combinations & Variations

Source Patent Element
Combination treatment method using anti-viral drugs and vaccines for coronavirus infection
PTD Variation
Applying combination treatment to plant disease prevention using pesticides and plant vaccines
Obviousness Reasoning
Known technique of synergistic intervention can be predictably extended to plant biological systems using analogous treatment principles
Source Patent Element
Administration schedule involving drug and vaccine timing (claims 4-5)
PTD Variation
Adapting administration protocols for bee colony and zoonotic disease prevention
Obviousness Reasoning
Timing and dosage strategies are transferable across biological intervention scenarios with minor contextual modifications
Source Patent Element
Anti-microbial drug combinations including zinc-based formulations
PTD Variation
Utilizing similar drug combination strategies for food safety and agricultural disease prevention
Obviousness Reasoning
Established pharmacological principles of combination therapy are universally applicable across different infection prevention contexts
Source Patent Element
Method for treating and preventing infectious conditions
PTD Variation
Expanding treatment methodology to address colony collapse disorder and crop disease mitigation
Obviousness Reasoning
Fundamental disease intervention strategy can be systematically adapted to different biological domains using known scientific translation techniques
Source Patent Element
Vaccine and drug combination targeting specific infectious agents
PTD Variation
Cross-domain application of combination treatment to zoonotic and agricultural infection scenarios
Obviousness Reasoning
Generalized treatment approach can be predictably modified for different biological systems using standard scientific translation methodologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857617, a person having ordinary skill in the art would find the variations disclosed in this publication obvious, as the fundamental combination treatment methodology can be systematically translated across biological domains using standard scientific techniques, thereby rendering obvious any claims attempting to limit such treatment strategies to specific contexts or applications.

Original Patent Information

Patent NumberUS 11,857,617
TitleMethods for treating, ameliorating or preventing infections using drug and vaccination combination treatment
Assignee(s)TOPELIA AUST LIMITED (652 771 670)