Intelligent Vaccine Enhancement System (IVES)

Publication ID: 24-11857618_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Intelligent Vaccine Enhancement System (IVES),” Published Technical Disclosure No. 24-11857618_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857618_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,618.

Summary of the Inventive Concept

IVES integrates AI, IoT, blockchain, and nanomaterials to create a personalized vaccine administration system, enhancing immunogenicity and improving vaccine efficacy in elderly and immune-suppressed populations.

Background and Problem Solved

The original patent addresses the issue of poor vaccine efficacy in elderly and immune-suppressed populations by using saponins and agonists of the intracellular stimulator of interferon genes pathway. However, it lacks the ability to monitor and predict immune responses, secure vaccination records, and provide personalized insights. IVES solves these limitations by incorporating AI-powered analytics, IoT sensors, blockchain-based data storage, and nanomaterial-based adjuvants to create a more effective and efficient vaccine administration system.

Detailed Description of the Inventive Concept

IVES consists of four primary components: 1) a vaccine administration module, 2) an AI-powered analytics module, 3) an IoT sensor module, and 4) a blockchain-based data storage module. The AI-powered analytics module processes data from the IoT sensors, genomic data, and medical history to generate personalized insights and recommendations for enhancing immune responses. The blockchain-based data storage module securely stores vaccination records, AI-generated insights, and genomic data. The nanomaterial-based adjuvants are designed to target specific immune cells, enhancing the immune response. IVES can be used for various vaccine types, including influenza, and can be integrated into existing healthcare systems.

Novelty and Inventive Step

The new claims introduce the integration of AI, IoT, blockchain, and nanomaterials to create a personalized vaccine administration system, which is not present in the original patent. The inventive step lies in the synergistic combination of these technologies to enhance immunogenicity and improve vaccine efficacy.

Alternative Embodiments and Variations

IVES can be implemented in various ways, such as using different AI algorithms, IoT sensor configurations, or blockchain platforms. Additionally, IVES can be adapted for use in different populations, such as pediatric or immune-competent individuals, or for various vaccine types, including cancer or infectious disease vaccines.

Potential Commercial Applications and Market

IVES has significant commercial potential in the vaccine industry, particularly in the elderly and immune-suppressed populations. The system can be marketed to healthcare providers, pharmaceutical companies, and government agencies, offering a more effective and efficient vaccine administration system. The market potential is substantial, with the global vaccine market projected to reach $64 billion by 2027.

CPC Classifications

SectionClassGroup
A A61 A61K39/145
A A61 A61K39/39
A A61 A61P31/16
A A61 A61K2039/55
A A61 A61K2039/55555
A A61 A61K2039/55561
A A61 A61K2039/55577

Original Patent Information

Patent NumberUS 11,857,618
TitleBoosting immunogenicity of vaccines using saponins and agonists of the intracellular stimulator of interferon genes pathway
Assignee(s)Emory University