Adenovirus-Mediated CoV2 Protein Expression for Diverse Industrial Applications

The present inventive concept leverages the core technology of the original patent to develop novel applications in agriculture, environmental remediation, food safety, and biofuel production, demonstrating the versatility and potential of adenovirus-mediated CoV2 protein expression.

The original patent focused on inducing immunity against SARS-CoV-2 using spike (S) and nucleocapsid (N)-ETSD immunogens delivered by a replication-defective adenovirus. However, this technology has broader implications and potential applications beyond human health. The present inventive concept addresses the limitations of the original patent by exploring new industries and use cases.

The new claims describe various applications of adenovirus-mediated CoV2 protein expression, including enhancing crop yields, reducing water pollution, detecting contaminants in food products, improving bioremediation of contaminated soil, and enhancing biofuel production. These applications involve the delivery of CoV2 spike or nucleocapsid proteins to plant cells, aquatic organisms, microorganisms, or yeast cells using replication-defective adenoviruses, which enables the expression of these proteins on the cell surface or within endosomes. This expression enhances specific biological processes, such as photosynthesis, nutrient uptake, pollutant degradation, and fermentation efficiency, leading to improved outcomes in the respective industries.

The new claims introduce a significant shift in the application of adenovirus-mediated CoV2 protein expression, moving from human health to diverse industrial sectors. The inventive step lies in recognizing the potential of this technology to address specific challenges in these industries and developing novel compositions and methods that achieve this.

Other embodiments of the inventive concept could involve the use of different viral vectors, protein modifications, or delivery methods to achieve similar outcomes in various industries. Additionally, the CoV2 proteins could be combined with other molecules or expressed in different cellular environments to further expand the range of applications.

The inventive concept has significant commercial potential in the agriculture, environmental remediation, food safety, and biofuel production industries, where it can improve crop yields, reduce pollution, enhance food safety, and increase biofuel production efficiency. The market for these applications is substantial, with potential customers including agricultural companies, environmental remediation services, food manufacturers, and biofuel producers.