Expanding Pan-antiallergy Vaccine Technology to New Applications
Legal Citation
Summary of the Inventive Concept
This inventive concept explores the application of the pan-antiallergy vaccine technology to novel fields, including cancer treatment, agricultural worker safety, neurodegenerative disease management, food product safety, and cardiovascular disease prevention.
Background and Problem Solved
The original pan-antiallergy vaccine patent addressed a significant need in the field of immunology. However, its scope was limited to treating allergies. This new inventive concept addresses the problem of underutilization of the core technology by applying it to entirely new industries and fields, thereby expanding its impact and potential benefits.
Detailed Description of the Inventive Concept
The new claims describe various applications of the pan-antiallergy vaccine technology. For instance, the protein construct can be used to induce an immune response against IgE in cancer treatment, reducing the risk of allergic reactions in agricultural workers, enhancing the delivery of neuroprotective agents across the blood-brain barrier, detecting IgE levels in food products, and reducing IgE-mediated inflammation in cardiovascular disease. These new applications leverage the core technology's ability to modulate the immune system, offering innovative solutions to pressing problems in diverse fields.
Novelty and Inventive Step
The new claims introduce a non-obvious expansion of the original patent's scope, applying the pan-antiallergy vaccine technology to novel fields and industries. This inventive step lies in the recognition of the technology's potential to address unmet needs beyond its original intended use.
Alternative Embodiments and Variations
Alternative embodiments of this inventive concept could include modifying the protein construct to target specific IgE subtypes, developing novel adjuvants or delivery mechanisms, or exploring combination therapies with existing treatments. Variations could also involve applying the technology to other diseases or conditions where IgE modulation is beneficial.
Potential Commercial Applications and Market
This inventive concept has significant commercial potential, with applications in the pharmaceutical, agricultural, and food industries. The market for these new applications is substantial, with potential users including cancer treatment centers, agricultural companies, neurology clinics, food manufacturers, and cardiovascular disease treatment providers.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K39/395 |
| A | A61 | A61K2039/544 |
| A | A61 | A61K2039/555 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Immunology, protein engineering, and vaccine development, with expertise in protein construct design, immune system modulation, and biotechnology applications
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in molecular biology or bioengineering, experienced in protein modification techniques, immunological assays, and cross-disciplinary therapeutic applications
Obviousness Rationale
A PHOSITA would recognize that the core protein construct technology from the source patent provides a versatile platform for immune system modulation that can be readily adapted to multiple therapeutic and diagnostic contexts. The fundamental mechanism of modifying a scaffold protein with an IgE motif creates a predictable template for exploring diverse medical applications. The disclosed variations represent logical extensions of the original vaccine technology by applying its core immunomodulatory principles to different disease states and biological challenges.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,623 |
|---|---|
| Title | Pan-antiallergy vaccine |
| Assignee(s) | King Abdulaziz University |