Personalized Allergy Treatment Ecosystem

Publication ID: 24-11857623_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Allergy Treatment Ecosystem,” Published Technical Disclosure No. 24-11857623_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857623_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,623.

Summary of the Inventive Concept

A comprehensive system integrating advanced genomics, machine learning, and nanotechnology to provide customized allergy diagnosis, treatment, and real-time monitoring, revolutionizing the field of immunology and allergy research.

Background and Problem Solved

The original pan-antiallergy vaccine patent, while groundbreaking, has limitations in terms of personalized treatment and real-time monitoring. The new inventive concept addresses these limitations by envisioning a next-generation allergy treatment ecosystem that leverages cutting-edge technologies to provide tailored solutions for individual patients.

Detailed Description of the Inventive Concept

The Personalized Allergy Treatment Ecosystem consists of multiple components, including a biomarker detection module, a treatment response prediction algorithm, a customized allergy vaccine generator, a wearable device for real-time allergy monitoring, and a cloud-based platform for allergy research and development. The system utilizes machine learning-based genomics analysis to identify an individual's specific allergy profile and synthesizes a vaccine composition comprising antigenic peptides specific to the identified allergens. The wearable device detects IgE levels and predicts allergic reactions, transmitting alerts to the user's device. The cloud-based platform facilitates collaboration among researchers and provides a database of genomic and proteomic data related to allergies.

Novelty and Inventive Step

The new inventive concept introduces a paradigm shift in allergy treatment by integrating personalized genomics, machine learning, and nanotechnology to provide a comprehensive and customized solution. The inventive step lies in the synergistic combination of these technologies to create a novel ecosystem that surpasses the capabilities of the original pan-antiallergy vaccine.

Alternative Embodiments and Variations

Alternative embodiments of the Personalized Allergy Treatment Ecosystem could include the use of different machine learning algorithms, various types of biomarkers, or alternative nanotechnology-based delivery systems. Variations of the system could also be designed for specific types of allergies or targeted towards particular demographics.

Potential Commercial Applications and Market

The Personalized Allergy Treatment Ecosystem has significant commercial potential in the pharmaceutical, biotechnology, and healthcare industries. The system could be marketed as a comprehensive solution for allergy treatment, offering a competitive advantage over existing treatments. The cloud-based platform could also generate revenue through subscription-based access to the database and collaboration tools.

CPC Classifications

SectionClassGroup
A A61 A61K39/395
A A61 A61K2039/544
A A61 A61K2039/555

Field of Art

Immunology, biotechnology, and personalized medicine, with expertise in protein engineering, vaccine design, and machine learning applications in medical diagnostics

Person of Ordinary Skill (PHOSITA) Profile

A researcher with advanced degrees in biotechnology or immunology, proficient in computational biology, protein modeling, machine learning techniques, and understanding of immunological systems and vaccine development

Obviousness Rationale

A PHOSITA would recognize that the personalized allergy treatment ecosystem represents a predictable extension of existing pan-antiallergy vaccine technologies by integrating known computational and diagnostic techniques. The combination of machine learning, genomic analysis, and targeted vaccine design follows established methodological approaches in precision medicine. The technical variations represent incremental improvements that would be obvious to a skilled practitioner seeking to enhance allergy treatment strategies.

Obvious Combinations & Variations

Source Patent Element
Protein construct with scaffold segment and motif segment for immunological intervention
PTD Variation
Machine learning-driven customization of vaccine composition using individual genomic biomarkers
Obviousness Reasoning
Predictable application of computational techniques to personalize existing protein engineering approaches, representing a known method of tailoring medical treatments to individual genetic profiles
Source Patent Element
EAP domain protein modification for immunological purposes
PTD Variation
Nanotechnology-based delivery system targeting IgE-producing cells with controlled release mechanism
Obviousness Reasoning
Logical extension of protein modification techniques using well-established nanotechnology approaches for targeted drug delivery, representing a finite set of predictable engineering solutions
Source Patent Element
Immunoglobulin E (IgE) related protein construct
PTD Variation
Real-time IgE level monitoring using wearable biosensor technology
Obviousness Reasoning
Obvious combination of known biosensor technologies with existing immunological understanding, representing a standard approach to continuous medical monitoring
Source Patent Element
Computer modeling of protein scaffold modifications
PTD Variation
Cloud-based platform for collaborative allergy research using machine learning predictive analytics
Obviousness Reasoning
Natural progression of computational techniques in medical research, utilizing standard data sharing and analysis methodologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857623 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed personalized allergy treatment ecosystem obvious through routine application of known computational, biotechnological, and medical monitoring techniques. The incremental innovations represent predictable combinations of existing technologies in immunology and precision medicine, thereby rendering subsequent claims obvious under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,623
TitlePan-antiallergy vaccine
Assignee(s)King Abdulaziz University