Personalized Cancer Therapy Platform using OPCML Fragment and AI

Publication ID: 24-11857624_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Personalized Cancer Therapy Platform using OPCML Fragment and AI,” Published Technical Disclosure No. 24-11857624_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857624_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,624.

Summary of the Inventive Concept

A novel system integrating OPCML fragment-based cancer therapy with AI-driven predictive modeling, IoT-enabled biosensors, blockchain-based data sharing, and novel nanomaterials for targeted delivery, enabling personalized and effective cancer treatment.

Background and Problem Solved

Cancer treatment is a complex and challenging field, with current methods often lacking personalized approaches. The original patent disclosed the use of OPCML fragment for cancer therapy, but it had limitations in terms of efficacy, dosage, and treatment duration. The new inventive concept addresses these limitations by synergistically combining the OPCML fragment with other distinct technologies.

Detailed Description of the Inventive Concept

The new system consists of four key components: 1) AI-based predictive modeling for personalized therapy, utilizing genomic profiles of patients with ovarian cancer; 2) IoT-enabled biosensors for real-time monitoring of cancer biomarkers, detecting changes in OPCML expression levels; 3) a blockchain-based platform for secure sharing of OPCML-related research data and collaboration among researchers; and 4) a novel composition of matter comprising OPCML fragment and a targeted delivery nanomaterial. These components work together to provide a comprehensive and personalized cancer treatment approach.

Novelty and Inventive Step

The new claims introduce a synergistic combination of OPCML fragment with AI, IoT, blockchain, and novel nanomaterials, which is not obvious from the original patent. The inventive step lies in the integration of these distinct technologies to create a more powerful and effective system for cancer treatment.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, various IoT-enabled devices, or alternative blockchain platforms. Additionally, the OPCML fragment could be combined with other cancer therapeutic agents or used in conjunction with different types of cancer.

Potential Commercial Applications and Market

The personalized cancer therapy platform has significant commercial potential in the oncology market, with potential applications in ovarian cancer treatment and beyond. The market for cancer therapy is projected to grow significantly in the coming years, and this inventive concept is well-positioned to capitalize on this trend.

CPC Classifications

SectionClassGroup
A A61 A61K39/39558
A A61 A61K31/404
A A61 A61K31/506
A A61 A61K31/517
A A61 A61K31/555
A A61 A61K31/7064
A A61 A61K38/1774
A A61 A61K45/06
C C07 C07K16/28
C C07 C07K16/2863
C C07 C07K16/32
C C12 C12Q1/6886
C C12 C12Q2600/118
C C12 C12Q2600/156
C C12 C12Q2600/158

Original Patent Information

Patent NumberUS 11,857,624
TitleCancer therapeutic methods utilizing OPCML fragment
Assignee(s)PAPYRUS THERAPEUTICS, INC.