Synergistic Cancer Therapeutic Systems

Publication ID: 24-11857624_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Cancer Therapeutic Systems,” Published Technical Disclosure No. 24-11857624_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857624_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,624.

Summary of the Inventive Concept

The present invention integrates OPCML-based cancer therapy with distinct technologies such as AI, IoT, blockchain, and nanomaterials to create a more powerful system for personalized cancer treatment, research, and data management.

Background and Problem Solved

Cancer is a leading cause of mortality worldwide, and current treatment options often have limited efficacy and significant side effects. The original patent disclosed the use of OPCML fragments for cancer therapy, but it lacked the scalability, precision, and security offered by modern technologies. The new inventive concept addresses these limitations by combining OPCML fragments with AI-driven recommendation engines, IoT-enabled wearable devices, blockchain-based data management platforms, and nanomaterial-based delivery vehicles.

Detailed Description of the Inventive Concept

The synergistic system comprises a database of OPCML fragments, which can be fused to non-OPCML polypeptides for enhanced efficacy. The AI-driven recommendation engine selects optimal treatment regimens based on patient-specific genomic data and OPCML fragment efficacy. IoT-enabled wearable devices enable real-time monitoring of treatment response and patient health, while the blockchain-based data management platform ensures secure and transparent sharing of research data and clinical trial results. The nanomaterial-based delivery vehicle facilitates targeted and controlled release of the OPCML fragment in cancer cells. This integrated system enables personalized cancer treatment, improves treatment outcomes, and accelerates research and development.

Novelty and Inventive Step

The new claims introduce the concept of integrating OPCML-based cancer therapy with distinct technologies, which is novel and non-obvious compared to the original patent. The use of AI, IoT, blockchain, and nanomaterials in conjunction with OPCML fragments provides a synergistic effect that enhances the efficacy, precision, and security of cancer treatment and research.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different AI algorithms, IoT devices, or blockchain platforms. Variations may involve the integration of OPCML fragments with other emerging technologies, such as CRISPR gene editing or synthetic biology.

Potential Commercial Applications and Market

The synergistic cancer therapeutic system has significant commercial potential in the pharmaceutical, biotechnology, and healthcare industries. It can be used for personalized cancer treatment, research, and data management, and has the potential to improve treatment outcomes, reduce healthcare costs, and accelerate the development of new cancer therapies.

CPC Classifications

SectionClassGroup
A A61 A61K39/39558
A A61 A61K31/404
A A61 A61K31/506
A A61 A61K31/517
A A61 A61K31/555
A A61 A61K31/7064
A A61 A61K38/1774
A A61 A61K45/06
C C07 C07K16/28
C C07 C07K16/2863
C C07 C07K16/32
C C12 C12Q1/6886
C C12 C12Q2600/118
C C12 C12Q2600/156
C C12 C12Q2600/158

Original Patent Information

Patent NumberUS 11,857,624
TitleCancer therapeutic methods utilizing OPCML fragment
Assignee(s)PAPYRUS THERAPEUTICS, INC.