Oxygen Therapeutics for Enhanced Industrial Processes

Publication ID: 24-11857627_0007_PTD

Published: October 28, 2025

Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Oxygen Therapeutics for Enhanced Industrial Processes,” Published Technical Disclosure No. 24-11857627_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857627_0007_PTD

This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,627.

Summary of the Inventive Concept

The inventive concept leverages the core technology of oxygen therapeutics to improve outcomes in various industrial processes, including agriculture, oil recovery, wastewater treatment, aquaculture, and bioreactors.

Background and Problem Solved

The original patent addressed the limitation of hypoxia in solid tumors, but the technology has broader applications. The inventive concept solves the problem of oxygen deficiencies in various industrial processes, leading to improved efficiency, productivity, and environmental sustainability.

Detailed Description of the Inventive Concept

The inventive concept involves administering oxygen therapeutics in combination with precision agriculture practices to improve crop yields, enhancing oil recovery by increasing oxygen levels in reservoirs, treating wastewater by increasing oxygen levels, reducing the environmental impact of aquaculture by administering oxygen therapeutics to the aquatic environment, and improving the efficiency of bioreactors by increasing oxygen levels. These applications leverage the oxygen therapeutic's ability to increase oxygen levels, thereby improving process outcomes.

Novelty and Inventive Step

The new claims introduce novel applications and use cases for the oxygen therapeutic technology, expanding its scope beyond cancer treatment to various industrial processes. The inventive step lies in recognizing the broader potential of the technology and adapting it to address specific challenges in these new fields.

Alternative Embodiments and Variations

Alternative embodiments may include different oxygen therapeutic formulations, administration methods, or sensor technologies to optimize oxygen levels. Variations may also involve integrating the oxygen therapeutic with existing industrial processes or developing new processes that take advantage of the technology's benefits.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including agriculture, oil and gas, wastewater treatment, aquaculture, and biotechnology. The market for oxygen therapeutics in these industries is substantial, with potential applications in improving crop yields, enhancing oil recovery, reducing wastewater treatment costs, promoting sustainable aquaculture, and increasing bioreactor efficiency.

CPC Classifications

Section	Class	Group
A	A61	A61K41/0038
A	A61	A61K9/0019
A	A61	A61K9/107
A	A61	A61K31/02
A	A61	A61K33/00
A	A61	A61K39/395
A	A61	A61K45/06
A	A61	A61K47/10
A	A61	A61K47/24
A	A61	A61K47/26
A	A61	A61N5/10
A	A61	A61K2039/505
A	A61	A61K2039/545
A	A61	A61N2005/1098

Section 103 Obviousness Analysis (PHOSITA)

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Field of Art

Medical and Chemical Engineering with a focus on oxygen therapeutics, drug delivery systems, and process optimization across biological and industrial applications

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in chemical engineering, biomedical engineering, or related fields, possessing expertise in oxygen delivery technologies, emulsion formulations, and cross-domain technology transfer

Obviousness Rationale

A PHOSITA would recognize that the core oxygen therapeutic technology disclosed in the source patent represents a fundamental platform technology with broad applicability beyond cancer treatment. The PTD's industrial process variations represent predictable extensions of the core oxygen delivery mechanism, leveraging the well-established principles of increasing oxygen bioavailability in complex systems. The technical principles of oxygen therapeutic administration are directly transferable across domains, making the proposed industrial applications a straightforward and obvious technological adaptation.

Obvious Combinations & Variations

Source Patent Element

Intravenous administration of perfluoropentane emulsion to increase oxygen levels in tumor environments

PTD Variation

Injecting oxygen therapeutic into soil, oil reservoirs, and aquatic environments to enhance oxygen levels

Obviousness Reasoning

Known technique of targeted oxygen delivery can be predictably applied to other oxygen-limited environments using standard injection and distribution methods

Source Patent Element

Precise dosage control and administration timing in medical treatments

PTD Variation

Using sensors and controllers to optimize oxygen therapeutic delivery in industrial processes

Obviousness Reasoning

Applying control system engineering principles to optimize oxygen delivery is a standard design choice with predictable technological implementation

Source Patent Element

Water-based emulsion containing 1-5% perfluoropentane for medical use

PTD Variation

Developing alternative emulsion formulations for agricultural, industrial, and environmental applications

Obviousness Reasoning

Modifying emulsion compositions for different target environments represents a routine engineering optimization with finite, predictable solution set

Source Patent Element

Multi-fraction delivery approach for radiotherapy

PTD Variation

Repeated, controlled oxygen therapeutic administration in bioreactors and aquaculture systems

Obviousness Reasoning

Extending the concept of periodic, controlled substance delivery to industrial bioprocessing is an obvious technological progression

Source Patent Element

Oxygen enhancement to improve cellular response in medical treatments

PTD Variation

Using oxygen therapeutics to improve process efficiency across agriculture, oil recovery, and wastewater treatment

Obviousness Reasoning

Recognizing oxygen's universal role in biological and chemical processes makes cross-domain technology transfer a predictable innovation

35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857627 and the published technical disclosure, a person of ordinary skill in the art would find the proposed industrial applications of oxygen therapeutics to be obvious variations of the existing medical technology, rendering potential patent claims in these domains anticipated and non-patentable under standard obviousness analysis.

Original Patent Information

Patent Number	US 11,857,627
Title	Fractionated radiotherapy and chemotherapy with an oxygen therapeutic
Assignee(s)	NuvOx Pharma LLC