pH-Dependent Release Mechanisms for Environmental Remediation and Monitoring

Publication ID: 24-11857629_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “pH-Dependent Release Mechanisms for Environmental Remediation and Monitoring,” Published Technical Disclosure No. 24-11857629_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857629_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,629.

Summary of the Inventive Concept

A novel application of pH-dependent release mechanisms, originally developed for abuse-deterrent pharmaceutical compositions, to address pressing environmental challenges, including pollution, oil spills, wildfires, agricultural pests, and industrial wastewater treatment.

Background and Problem Solved

The original patent disclosed pH-dependent release mechanisms for abuse-deterrent pharmaceutical compositions. However, the limitations of this technology were confined to pharmaceutical applications. The new inventive concept addresses the pressing need for innovative solutions to environmental problems by adapting the core technology to novel use cases.

Detailed Description of the Inventive Concept

The new inventive concept leverages the pH-dependent release mechanism to encapsulate remediation agents, pesticides, fire-suppressing agents, or other environmentally beneficial substances. These agents are released in response to specific pH levels indicative of environmental pollution, oil spills, wildfires, pest presence, or wastewater contamination. The buffering ingredient retards the release of the acid soluble ingredient until the predetermined pH level is reached, ensuring targeted and controlled delivery of the remediation agents.

Novelty and Inventive Step

The new inventive concept introduces a paradigm shift by applying the pH-dependent release mechanism to entirely new industries and problems, demonstrating a non-obvious and innovative adaptation of the original technology.

Alternative Embodiments and Variations

Alternative embodiments may include using different types of buffering ingredients, acid soluble ingredients, or encapsulation materials. Variations could involve adapting the pH-dependent release mechanism for use in other environmental applications, such as monitoring and controlling air pollution or detecting and responding to natural disasters.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in various environmental industries, including pollution remediation, oil spill response, wildfire management, agricultural pest control, and industrial wastewater treatment. The market for these applications is substantial, with growing demand for innovative, targeted, and environmentally responsible solutions.

CPC Classifications

SectionClassGroup
A A61 A61K47/02
A A61 A61K9/2009
A A61 A61K9/2027
A A61 A61K9/2077
A A61 A61K31/5517
A A61 A61K47/32

Original Patent Information

Patent NumberUS 11,857,629
TitleMethods and compositions for self-regulated release of active pharmaceutical ingredient
Assignee(s)Acurx Pharmaceuticals, Inc.