Synergistic Abuse Deterrent Pharmaceutical Systems

Publication ID: 24-11857629_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Abuse Deterrent Pharmaceutical Systems,” Published Technical Disclosure No. 24-11857629_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857629_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,629.

Summary of the Inventive Concept

Integrating abuse deterrent pharmaceutical compositions with AI, IoT, blockchain, and nanomaterials to create a more powerful system for preventing drug abuse and ensuring personalized drug delivery.

Background and Problem Solved

The original patent disclosed abuse deterrent pharmaceutical compositions that addressed opioid abuse. However, these compositions had limitations in tracking and controlling dosage, as well as ensuring personalized delivery. The new inventive concept addresses these limitations by synergistically combining the abuse deterrent pharmaceutical composition with distinct technologies to create a more robust system.

Detailed Description of the Inventive Concept

The new inventive concept comprises a synergistic combination of an abuse deterrent pharmaceutical composition and one or more of the following: AI-powered dosage tracking devices, blockchain-secured, IoT-enabled pharmaceutical compositions, pH-dependent solubility features, nanomaterial-based delivery systems, pH-modifying features, microchip-enabled tracking devices, and AI-powered genomic analysis tools. These components work together to monitor and control the release of the pharmaceutically active ingredient, track and verify dosage, and predict user response to the pharmaceutically active ingredient.

Novelty and Inventive Step

The new claims introduce a synergistic combination of distinct technologies that provides a more robust system for preventing drug abuse and ensuring personalized drug delivery. The integration of these technologies with the abuse deterrent pharmaceutical composition is new and non-obvious compared to the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include integrating the abuse deterrent pharmaceutical composition with other technologies, such as machine learning algorithms, wearable devices, or cloud-based data analytics platforms. Variations may include using different types of nanomaterials, pH-modifying features, or genomic analysis tools.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical industry, particularly in the areas of opioid abuse prevention and personalized drug delivery. Target markets may include pharmaceutical companies, healthcare providers, and government agencies focused on addressing the opioid epidemic.

CPC Classifications

SectionClassGroup
A A61 A61K47/02
A A61 A61K9/2009
A A61 A61K9/2027
A A61 A61K9/2077
A A61 A61K31/5517
A A61 A61K47/32

Original Patent Information

Patent NumberUS 11,857,629
TitleMethods and compositions for self-regulated release of active pharmaceutical ingredient
Assignee(s)Acurx Pharmaceuticals, Inc.