Published Technical Disclosure Archive

Poly(amino acid) block polymer-based solutions for diverse industries

Publication ID: 24-11857630_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Poly(amino acid) block polymer-based solutions for diverse industries,” Published Technical Disclosure No. 24-11857630_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857630_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,630.

Summary of the Inventive Concept

This inventive concept leverages the core technology of SN-38 and poly(amino acid) block polymer formulations to address critical challenges in wastewater treatment, medical devices, agricultural applications, and aquatic ecosystems.

Background and Problem Solved

The original patent disclosed formulations of SN-38 with poly(amino acid) block polymers for pharmaceutical applications. However, the patent's scope was limited to the pharmaceutical industry. The new inventive concept expands the application of this technology to tackle pressing issues in other industries, such as the growth of microorganisms in wastewater treatment, biofilm formation on medical devices, pest and disease control in agriculture, and invasive species management in aquatic ecosystems.

Detailed Description of the Inventive Concept

The new inventive concept involves the use of SN-38 and poly(amino acid) block polymer compositions in various industries. In wastewater treatment, the composition inhibits microorganism growth, improving treatment efficiency and reducing environmental impact. In medical devices, the composition is used as a coating to prevent biofilm formation, reducing the risk of infections. In agricultural applications, the composition controls pests and diseases in crops, enhancing yields and reducing chemical usage. In aquatic ecosystems, the composition is used to control invasive species, preserving biodiversity and ecosystem balance.

Novelty and Inventive Step

The new claims introduce novel applications and use cases for the SN-38 and poly(amino acid) block polymer technology, which were not contemplated in the original patent. The inventive step lies in recognizing the potential of this technology to address diverse industry challenges and developing specific formulations and methods to achieve this.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include different poly(amino acid) block polymer structures, varying ratios of SN-38 to polymer, and diverse application methods. Additionally, the technology could be adapted for use in other industries, such as cosmetics, textiles, or food processing.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential, with applications in wastewater treatment, medical devices, agricultural applications, and aquatic ecosystems. The target market includes companies and organizations operating in these industries, as well as government agencies responsible for environmental protection and public health.

CPC Classifications

SectionClassGroup
A A61 A61K47/34
A A61 A61K9/08
A A61 A61K9/19
A A61 A61K31/4375
A A61 A61K31/513
A A61 A61K31/519
A A61 A61K45/06
A A61 A61K47/26

Field of Art

Pharmaceutical formulations, drug delivery systems, and polymer-based compositions with a focus on bioactive compounds and their applications in medical, environmental, and agricultural technologies

Person of Ordinary Skill (PHOSITA) Profile

A researcher with advanced degrees in polymer chemistry, pharmaceutical sciences, or chemical engineering, possessing expertise in drug formulation, polymer synthesis, and interdisciplinary applications of bioactive compounds

Obviousness Rationale

A person having ordinary skill in the art would recognize the inherent versatility of SN-38 and poly(amino acid) block polymers as a fundamental platform technology with broad potential applications. The source patent establishes the core compositional framework, which a skilled practitioner would naturally explore for alternative uses by leveraging the known antimicrobial and inhibitory properties of the compound. The PTD's proposed variations represent predictable extensions of the original technological concept, utilizing standard techniques of formulation and application adaptation.

Obvious Combinations & Variations

Source Patent Element
Composition of SN-38 with poly(amino acid) block copolymer
PTD Variation
Application of the composition for wastewater treatment microorganism inhibition
Obviousness Reasoning
A PHOSITA would recognize the antimicrobial properties of SN-38 and understand its potential for controlling microbial growth across different environments as a predictable design choice
Source Patent Element
Specific weight ratios of SN-38 to polymer (1-30% SN-38, 10-90% polymer)
PTD Variation
Adapting composition ratios for agricultural pest control and medical device coatings
Obviousness Reasoning
The source patent's established compositional ranges provide a clear framework for modifying concentrations to suit different technical applications, representing a routine optimization process
Source Patent Element
Poly(amino acid) block polymer formulation with potential protective properties
PTD Variation
Using composition for biofilm prevention on medical devices
Obviousness Reasoning
The inherent antimicrobial and binding characteristics of the polymer system suggest a predictable extension to preventing microbial adhesion, which would be an obvious solution to a PHOSITA
Source Patent Element
Chemical structure allowing interaction with biological systems
PTD Variation
Controlling invasive species in aquatic ecosystems
Obviousness Reasoning
The fundamental mechanism of SN-38 as a biological inhibitor naturally suggests potential applications in ecosystem management, representing a logical and foreseeable technological progression
Source Patent Element
Broad potential for polymer-drug interactions
PTD Variation
Exploring alternative industries like agricultural and environmental technologies
Obviousness Reasoning
A PHOSITA would recognize the versatility of the compositional system and be motivated to explore diverse application domains as a standard approach to technological innovation
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857630, the present publication demonstrates that the claimed variations in SN-38 and poly(amino acid) block polymer compositions represent obvious extensions of the prior art, rendering subsequent claims directed to similar formulations and methods prima facie obvious under 35 U.S.C. ยง 103. The disclosed technological adaptations emerge from routine design choices and predictable applications of the established compositional framework, which would be readily apparent to a person having ordinary skill in pharmaceutical and polymer technologies.

Original Patent Information

Patent NumberUS 11,857,630
TitleFormulations of SN-38 with poly(amino acid) block polymers
Assignee(s)TYNDALL FORMULATION SERVICES, LLC