Intelligent Wound Healing System with Integrated AI, IoT, Blockchain, and New Materials

Publication ID: 24-11857631_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Intelligent Wound Healing System with Integrated AI, IoT, Blockchain, and New Materials,” Published Technical Disclosure No. 24-11857631_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857631_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,631.

Summary of the Inventive Concept

A novel wound healing system integrating a hydrogel-based therapeutic protein delivery system with AI, IoT, blockchain, and new materials to provide personalized, real-time monitoring, and optimized treatment outcomes.

Background and Problem Solved

The original patent disclosed a composition for delivering multiple therapeutic proteins for wound healing. However, the patent had limitations in terms of monitoring wound healing progress, adjusting treatment protocols, and securely storing patient data. The new inventive concept addresses these limitations by integrating the original composition with AI, IoT, blockchain, and new materials to provide a more comprehensive and effective wound healing system.

Detailed Description of the Inventive Concept

The new system comprises a hydrogel with a complex or coacervate of a polycationic polymer, a polyanionic polymer, fibroblast growth factor 2 (FGF-2), and stromal cell-derived factor 1 alpha (SDF-1α). The system integrates with an AI-powered monitoring device to track wound healing progress and adjust treatment protocols accordingly. Additionally, the system utilizes blockchain technology to securely store and share patient treatment data. The system also integrates with an IoT network to remotely monitor and adjust treatment protocols in real-time. Furthermore, the system utilizes machine learning algorithms to predict optimal treatment protocols based on patient data and integrates with new materials for customized wound dressings.

Novelty and Inventive Step

The new claims introduce the integration of AI, IoT, blockchain, and new materials with the original composition, providing a novel and non-obvious solution for wound healing. The inventive step lies in the synergistic combination of these distinct technologies to create a more comprehensive and effective wound healing system.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include integrating the system with other technologies such as robotics, 3D printing, or nanotechnology. Variations of the system could include using different types of polymers, growth factors, or new materials to customize the system for specific wound types or patient needs.

Potential Commercial Applications and Market

The intelligent wound healing system has significant commercial potential in the wound care industry, with applications in hospitals, clinics, and home healthcare settings. The system could be marketed to healthcare providers, medical device companies, and pharmaceutical companies, with potential revenue streams from device sales, data analytics services, and licensing agreements.

CPC Classifications

SectionClassGroup
A A61 A61K47/36
A A61 A61K9/0019
A A61 A61K9/06
A A61 A61K35/16
A A61 A61K35/19
A A61 A61K38/177
A A61 A61K38/18
A A61 A61K38/1825
A A61 A61K38/195
A A61 A61K47/34
A A61 A61K47/42
A A61 A61L15/225
A A61 A61L15/40
A A61 A61L15/44
A A61 A61L27/18
A A61 A61L27/20
A A61 A61L27/225
A A61 A61L27/26
A A61 A61L27/3616
A A61 A61L27/52
A A61 A61L27/54
A A61 A61L27/56
A A61 A61L31/041
A A61 A61L31/042
A A61 A61L31/046
A A61 A61L31/145
A A61 A61L31/16
A A61 A61P9/10
A A61 A61L2300/25
A A61 A61L2300/252
A A61 A61L2300/414
A A61 A61L2300/418
A A61 A61L2400/04
A A61 A61L2430/20

Field of Art

Biomedical engineering, specifically wound healing technologies, biomaterials, and protein delivery systems with expertise in polymer chemistry, growth factor formulation, and advanced medical device integration

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or materials scientist with advanced degree, working knowledge of hydrogel compositions, protein stabilization techniques, and emerging medical technologies, capable of understanding complex biomaterial interactions and technological convergence

Obviousness Rationale

A PHOSITA would recognize that integrating digital technologies with established protein delivery systems represents a natural progression of biomedical innovation. The core hydrogel composition remains substantially unchanged from the source patent, with technological additions representing predictable extensions of existing wound healing approaches. The combination of AI, IoT, and blockchain with established protein delivery mechanisms would be viewed as an incremental and obvious technological enhancement.

Obvious Combinations & Variations

Source Patent Element
Hydrogel composition with polycationic polymer, polyanionic polymer, FGF-2, and SDF-1α
PTD Variation
Adding AI-powered monitoring and machine learning treatment optimization
Obviousness Reasoning
Applying computational intelligence to medical device monitoring represents a known technique in personalized medicine, with predictable results of improved treatment tracking
Source Patent Element
Complex protein delivery system using specific polymer configurations
PTD Variation
Integrating blockchain for secure patient data management
Obviousness Reasoning
Implementing secure data tracking is a standard design choice in modern medical technologies, representing an obvious extension of existing medical record management practices
Source Patent Element
Wound healing composition with multiple therapeutic proteins
PTD Variation
IoT network integration for remote treatment protocol adjustment
Obviousness Reasoning
Remote monitoring of medical treatments is a well-established technological approach, representing a predictable application of existing telecommunications and medical monitoring technologies
Source Patent Element
Polycationic polymer with specific peptide configurations
PTD Variation
Customizable wound dressing materials using machine learning algorithms
Obviousness Reasoning
Adaptive material design using computational techniques is a known approach in materials engineering, representing a finite and predictable solution set
Source Patent Element
Protein stabilization using polymer complexes
PTD Variation
Integrating nanotechnology and advanced material science for wound healing
Obviousness Reasoning
Exploring material science innovations for medical applications is a standard research approach, with predictable outcomes of enhanced treatment capabilities
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857631 and the disclosed technological variations, a person of ordinary skill in the art would find the proposed wound healing system variations obvious and non-patentable. The incremental technological additions represent predictable extensions of existing protein delivery and medical monitoring technologies, lacking the requisite non-obviousness for novel patent protection.

Original Patent Information

Patent NumberUS 11,857,631
TitleProtection and delivery of multiple therapeutic proteins
Assignee(s)UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION