Synergistic Wound Healing System
Legal Citation
Summary of the Inventive Concept
A novel, integrated system for wound healing that combines a hydrogel composition with distinct technologies such as AI, IoT, blockchain, and novel biomaterials to provide personalized, real-time treatment and monitoring.
Background and Problem Solved
Current wound healing treatments are limited by the short half-lives and high costs of therapeutic proteins. The original patent addressed this issue by developing a hydrogel composition that protects and delivers multiple therapeutic proteins. However, this invention has limitations in terms of real-time monitoring and personalized treatment. The new inventive concept integrates the original hydrogel composition with AI, IoT, blockchain, and novel biomaterials to overcome these limitations.
Detailed Description of the Inventive Concept
The synergistic wound healing system consists of a hydrogel composition embedded with a complex or coacervate of a polycationic polymer, a polyanionic polymer, and a therapeutic protein. This composition is integrated with an AI-powered monitoring device that tracks wound healing progress and adjusts protein release accordingly. The system also includes an IoT-enabled sensor to monitor protein release and adjust the composition in real-time. Additionally, the system is integrated with a blockchain-based data management platform that securely tracks patient data and treatment outcomes. The composition may further comprise novel biomaterials such as graphene oxide, nanocellulose, and polyhydroxyalkanoates. The system may also utilize machine learning algorithms to analyze a patient's genetic profile and wound characteristics, generating a customized hydrogel composition tailored to the patient's specific needs.
Novelty and Inventive Step
The new claims introduce the integration of AI, IoT, blockchain, and novel biomaterials with the original hydrogel composition, providing a synergistic system that offers real-time monitoring, personalized treatment, and secure data management. This integration is non-obvious and novel compared to the original patent.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept may include different AI algorithms, IoT sensor configurations, blockchain platforms, and biomaterials. Variations of the system may also be developed for specific wound types, such as diabetic foot ulcers or burn wounds.
Potential Commercial Applications and Market
The synergistic wound healing system has significant commercial potential in the wound care industry, which is projected to reach $22.8 billion by 2025. The system's ability to provide personalized, real-time treatment and monitoring will appeal to hospitals, clinics, and patients seeking advanced wound care solutions.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K47/36 |
| A | A61 | A61K9/0019 |
| A | A61 | A61K9/06 |
| A | A61 | A61K35/16 |
| A | A61 | A61K35/19 |
| A | A61 | A61K38/177 |
| A | A61 | A61K38/18 |
| A | A61 | A61K38/1825 |
| A | A61 | A61K38/195 |
| A | A61 | A61K47/34 |
| A | A61 | A61K47/42 |
| A | A61 | A61L15/225 |
| A | A61 | A61L15/40 |
| A | A61 | A61L15/44 |
| A | A61 | A61L27/18 |
| A | A61 | A61L27/20 |
| A | A61 | A61L27/225 |
| A | A61 | A61L27/26 |
| A | A61 | A61L27/3616 |
| A | A61 | A61L27/52 |
| A | A61 | A61L27/54 |
| A | A61 | A61L27/56 |
| A | A61 | A61L31/041 |
| A | A61 | A61L31/042 |
| A | A61 | A61L31/046 |
| A | A61 | A61L31/145 |
| A | A61 | A61L31/16 |
| A | A61 | A61P9/10 |
| A | A61 | A61L2300/25 |
| A | A61 | A61L2300/252 |
| A | A61 | A61L2300/414 |
| A | A61 | A61L2300/418 |
| A | A61 | A61L2400/04 |
| A | A61 | A61L2430/20 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biomaterials, wound healing technologies, drug delivery systems, with expertise in polymer chemistry, protein engineering, and medical device integration
Person of Ordinary Skill (PHOSITA) Profile
A biomedical engineer or materials scientist with advanced degree, working knowledge of hydrogel compositions, protein delivery mechanisms, and emerging medical technologies, familiar with interdisciplinary approaches to wound healing interventions
Obviousness Rationale
A PHOSITA would recognize that integrating digital monitoring technologies and advanced biomaterials with existing hydrogel protein delivery systems represents a predictable extension of known wound healing approaches. The core hydrogel composition remains substantially similar to the source patent, with added technological layers that enhance monitoring and personalization. These technological integrations would be considered routine optimization within the field of advanced wound healing technologies.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,631 |
|---|---|
| Title | Protection and delivery of multiple therapeutic proteins |
| Assignee(s) | UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |