Next-Generation Wound Healing Platform
Legal Citation
Summary of the Inventive Concept
A comprehensive wound healing platform leveraging advanced biomaterials, micro-needling, and AI-driven personalized medicine to revolutionize wound care.
Background and Problem Solved
The original patent's composition of a hydrogel and complex/coacervate of polycationic and polyanionic polymers with therapeutic proteins, while effective, has limitations in terms of controlled release, delivery, and patient-specific customization. The new inventive concept addresses these limitations by introducing a system for controlled release of multiple therapeutic proteins, micro-needling devices, and AI-driven personalized medicine.
Detailed Description of the Inventive Concept
The next-generation wound healing platform consists of a matrix of bio-responsive polymers that release proteins in response to changes in pH, temperature, or ionic strength. The composition is administered using a micro-needling device, which enables transdermal delivery and minimizes invasiveness. The system is integrated with a wearable patch and a database of patient-specific wound characteristics, allowing for computational modeling and prediction of optimal therapeutic protein release profiles. Machine learning algorithms and data from a plurality of sensors enable real-time adjustments to the composition and delivery regimen.
Novelty and Inventive Step
The new claims introduce the concept of bio-responsive polymers, micro-needling devices, and AI-driven personalized medicine, which are novel and non-obvious compared to the original patent. The combination of these elements enables a more efficient, effective, and patient-specific wound healing process.
Alternative Embodiments and Variations
Alternative embodiments may include the use of different bio-responsive polymers, micro-needling devices with varying geometries, or alternative sensors and data sources for personalized medicine. Variations may also include the integration of additional therapeutic agents or the development of implantable devices for sustained release.
Potential Commercial Applications and Market
The next-generation wound healing platform has significant commercial potential in the wound care market, with potential applications in hospitals, clinics, and home care settings. The platform's ability to provide personalized medicine and improve patient outcomes may lead to increased adoption and market share.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K47/36 |
| A | A61 | A61K9/0019 |
| A | A61 | A61K9/06 |
| A | A61 | A61K35/16 |
| A | A61 | A61K35/19 |
| A | A61 | A61K38/177 |
| A | A61 | A61K38/18 |
| A | A61 | A61K38/1825 |
| A | A61 | A61K38/195 |
| A | A61 | A61K47/34 |
| A | A61 | A61K47/42 |
| A | A61 | A61L15/225 |
| A | A61 | A61L15/40 |
| A | A61 | A61L15/44 |
| A | A61 | A61L27/18 |
| A | A61 | A61L27/20 |
| A | A61 | A61L27/225 |
| A | A61 | A61L27/26 |
| A | A61 | A61L27/3616 |
| A | A61 | A61L27/52 |
| A | A61 | A61L27/54 |
| A | A61 | A61L27/56 |
| A | A61 | A61L31/041 |
| A | A61 | A61L31/042 |
| A | A61 | A61L31/046 |
| A | A61 | A61L31/145 |
| A | A61 | A61L31/16 |
| A | A61 | A61P9/10 |
| A | A61 | A61L2300/25 |
| A | A61 | A61L2300/252 |
| A | A61 | A61L2300/414 |
| A | A61 | A61L2300/418 |
| A | A61 | A61L2400/04 |
| A | A61 | A61L2430/20 |
Original Patent Information
| Patent Number | US 11,857,631 |
|---|---|
| Title | Protection and delivery of multiple therapeutic proteins |
| Assignee(s) | UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |