Next-Generation Wound Healing Platform

Publication ID: 24-11857631_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Generation Wound Healing Platform,” Published Technical Disclosure No. 24-11857631_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857631_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,631.

Summary of the Inventive Concept

A comprehensive wound healing platform leveraging advanced biomaterials, micro-needling, and AI-driven personalized medicine to revolutionize wound care.

Background and Problem Solved

The original patent's composition of a hydrogel and complex/coacervate of polycationic and polyanionic polymers with therapeutic proteins, while effective, has limitations in terms of controlled release, delivery, and patient-specific customization. The new inventive concept addresses these limitations by introducing a system for controlled release of multiple therapeutic proteins, micro-needling devices, and AI-driven personalized medicine.

Detailed Description of the Inventive Concept

The next-generation wound healing platform consists of a matrix of bio-responsive polymers that release proteins in response to changes in pH, temperature, or ionic strength. The composition is administered using a micro-needling device, which enables transdermal delivery and minimizes invasiveness. The system is integrated with a wearable patch and a database of patient-specific wound characteristics, allowing for computational modeling and prediction of optimal therapeutic protein release profiles. Machine learning algorithms and data from a plurality of sensors enable real-time adjustments to the composition and delivery regimen.

Novelty and Inventive Step

The new claims introduce the concept of bio-responsive polymers, micro-needling devices, and AI-driven personalized medicine, which are novel and non-obvious compared to the original patent. The combination of these elements enables a more efficient, effective, and patient-specific wound healing process.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different bio-responsive polymers, micro-needling devices with varying geometries, or alternative sensors and data sources for personalized medicine. Variations may also include the integration of additional therapeutic agents or the development of implantable devices for sustained release.

Potential Commercial Applications and Market

The next-generation wound healing platform has significant commercial potential in the wound care market, with potential applications in hospitals, clinics, and home care settings. The platform's ability to provide personalized medicine and improve patient outcomes may lead to increased adoption and market share.

CPC Classifications

SectionClassGroup
A A61 A61K47/36
A A61 A61K9/0019
A A61 A61K9/06
A A61 A61K35/16
A A61 A61K35/19
A A61 A61K38/177
A A61 A61K38/18
A A61 A61K38/1825
A A61 A61K38/195
A A61 A61K47/34
A A61 A61K47/42
A A61 A61L15/225
A A61 A61L15/40
A A61 A61L15/44
A A61 A61L27/18
A A61 A61L27/20
A A61 A61L27/225
A A61 A61L27/26
A A61 A61L27/3616
A A61 A61L27/52
A A61 A61L27/54
A A61 A61L27/56
A A61 A61L31/041
A A61 A61L31/042
A A61 A61L31/046
A A61 A61L31/145
A A61 A61L31/16
A A61 A61P9/10
A A61 A61L2300/25
A A61 A61L2300/252
A A61 A61L2300/414
A A61 A61L2300/418
A A61 A61L2400/04
A A61 A61L2430/20

Original Patent Information

Patent NumberUS 11,857,631
TitleProtection and delivery of multiple therapeutic proteins
Assignee(s)UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION