Synergistic Phosphorothioate-conjugated miRNA Systems
Legal Citation
Summary of the Inventive Concept
This inventive concept integrates phosphorothioate-conjugated miRNAs with AI, IoT, blockchain, and other technologies to create powerful systems for treating diseases, personalized medicine, and non-invasive diagnostics.
Background and Problem Solved
The original patent disclosed phosphorothioate-conjugated miRNAs for treating multiple myeloma and inhibiting IL-6 signaling. However, these methods have limitations in terms of treatment outcomes, patient profiling, and data security. The new inventive concept addresses these limitations by combining the patented miRNA technology with synergistic technologies to create more effective and efficient systems.
Detailed Description of the Inventive Concept
The inventive concept comprises a microRNA-based therapy module, an AI-driven patient profiling module, and a blockchain-secured data storage module. The microRNA-based therapy module utilizes phosphorothioate-conjugated miRNAs to treat diseases such as multiple myeloma. The AI-driven patient profiling module analyzes patient data to optimize treatment outcomes. The blockchain-secured data storage module ensures secure sharing of genomic data. Additionally, IoT-enabled sensors and machine learning algorithms are integrated to collect and analyze patient data, predict treatment efficacy, and monitor treatment outcomes.
Novelty and Inventive Step
The new inventive concept is novel and non-obvious because it combines the patented miRNA technology with distinct technologies such as AI, IoT, and blockchain to create synergistic systems that are more powerful and effective than the original patent. The inventive concept's integration of these technologies provides a new and innovative solution to the problems of treatment outcomes, patient profiling, and data security.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include integrating the microRNA-based therapy module with other AI-driven systems, such as decision support systems or natural language processing systems. Variations could include using different types of conjugated miRNAs or incorporating additional technologies such as nanotechnology or gene editing.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the fields of personalized medicine, disease treatment, and non-invasive diagnostics. The market for these applications is expected to grow rapidly in the coming years, driven by the increasing demand for more effective and efficient healthcare solutions.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K47/549 |
| A | A61 | A61K47/548 |
| A | A61 | A61K48/00 |
| C | C12 | C12N15/113 |
| C | C12 | C12N2310/141 |
| C | C12 | C12N2320/30 |
Original Patent Information
| Patent Number | US 11,857,633 |
|---|---|
| Title | Phosphorothioate-conjugated miRNAs and methods of using the same |
| Assignee(s) | City of Hope |