Specialized Cationic Amphiphilic Polymers for Targeted Delivery in Niche Environments
Legal Citation
Summary of the Inventive Concept
A novel adaptation of cationic amphiphilic polymers for co-delivery of hydrophobic agents and nucleic acids in high-security, disaster relief, extreme weather, high-altitude, and remote areas, providing enhanced bioavailability and targeted delivery
Background and Problem Solved
The original patent disclosed cationic amphiphilic polymers for co-delivery of hydrophobic agents and nucleic acids, but it did not address the specific challenges of delivering these agents in niche environments. The new inventive concept addresses this limitation by adapting the polymers for use in high-security facilities, disaster relief zones, extreme weather conditions, high-altitude environments, and remote areas, ensuring targeted delivery and enhanced bioavailability
Detailed Description of the Inventive Concept
The new inventive concept involves the design of specialized cationic amphiphilic polymers with hydrophobic polymer backbones and pendant groups tailored for specific niche environments. For high-security facilities, the polymers are equipped with tracking devices for monitoring delivery. In disaster relief zones, the polymers are adapted for use in extreme weather conditions. For areas with limited medical infrastructure, the polymers are designed for delivery via portable devices. In high-altitude environments, the polymers are adapted for low-oxygen conditions. For remote areas, the polymers are designed for delivery via unmanned aerial vehicles. These adaptations enable targeted delivery and enhanced bioavailability of hydrophobic agents and nucleic acids in these niche environments
Novelty and Inventive Step
The new inventive concept is novel and non-obvious because it adapts the original cationic amphiphilic polymers for use in specific niche environments, which was not contemplated in the original patent. The inventive step lies in the tailored design of the polymers for each environment, which enables targeted delivery and enhanced bioavailability
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include adaptations for other niche environments, such as underwater delivery or delivery in space. Variations could include different types of tracking devices, portable devices, or navigation systems
Potential Commercial Applications and Market
The new inventive concept has significant commercial potential in various industries, including pharmaceuticals, biotechnology, disaster relief, and remote healthcare. The targeted delivery of hydrophobic agents and nucleic acids in niche environments could revolutionize the treatment of diseases in these areas, providing a significant market opportunity
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K47/58 |
| A | A61 | A61K9/1075 |
| A | A61 | A61K31/65 |
| A | A61 | A61K47/549 |
| C | C12 | C12N15/113 |
| C | C12 | C12N2310/14 |
| C | C12 | C12N2310/351 |
Original Patent Information
| Patent Number | US 11,857,634 |
|---|---|
| Title | Cationic amphiphilic polymers for codelivery of hydrophobic agents and nucleic acids |
| Assignee(s) | UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |