Bio-Orthogonal Pesticide Activation in Food Processing

Publication ID: 24-11857636_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Bio-Orthogonal Pesticide Activation in Food Processing,” Published Technical Disclosure No. 24-11857636_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857636_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,636.

Summary of the Inventive Concept

This inventive concept leverages the core technology of bio-orthogonal drug activation to develop novel systems, methods, and devices for pesticide management in food processing environments, enhancing food safety and reducing pesticide residues.

Background and Problem Solved

The original patent on bio-orthogonal drug activation has been successful in addressing the limitations of traditional prodrug activation methods. However, the agricultural industry faces unique challenges in managing pesticide residues in food products. Current methods often result in excessive pesticide use, environmental contamination, and health risks. This inventive concept tackles these issues by applying the bio-orthogonal technology to pesticide activation in food processing environments, providing a targeted, efficient, and safer approach to pesticide management.

Detailed Description of the Inventive Concept

The inventive concept involves the use of bio-orthogonal, abiotic chemical reactions to activate prodrug pesticides in food processing environments. This is achieved through a system comprising a reaction chamber, a compatible diene, and a sensor for detecting the activated pesticide. The reaction occurs in the presence of the compatible diene, ensuring targeted and controlled activation of the pesticide. The sensor enables real-time monitoring of pesticide levels, allowing for optimized pesticide use and reduced residues in food products. The inventive concept also encompasses methods for reducing pesticide residues, improving food safety, and monitoring pesticide levels, as well as devices for reducing pesticide contamination in food processing environments.

Novelty and Inventive Step

The new claims introduce a novel application of bio-orthogonal technology in the agricultural industry, specifically in food processing environments. The inventive concept's use of bio-orthogonal reactions for pesticide activation, combined with the targeted and controlled nature of the system, provides a non-obvious solution to the problems faced by the agricultural industry.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include variations in the reaction chamber design, different compatible dienes, or alternative sensors for detecting activated pesticides. Additionally, the inventive concept could be adapted for use in other industries, such as environmental remediation or biomedical applications.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the agricultural industry, particularly in the food processing and safety sectors. The technology could be licensed to companies involved in food production, processing, and safety, or used to develop new products and services for the agricultural market.

CPC Classifications

SectionClassGroup
A A61 A61K47/6803
A A61 A61K31/435
A A61 A61K31/444
A A61 A61K31/704
A A61 A61K38/05
A A61 A61K39/3955
A A61 A61K39/39558
A A61 A61K47/22
A A61 A61K47/545
A A61 A61K47/555
A A61 A61K47/558
A A61 A61K47/6897
B B82 B82Y5/00
C C07 C07C33/16
C C07 C07D237/26
C C07 C07D257/08
Y Y02 Y02A50/30

Original Patent Information

Patent NumberUS 11,857,636
TitleBio-orthogonal drug activation
Assignee(s)Tagworks Pharmaceuticals B.V.