Novel Applications of Anti-CD25 Antibody-Maytansine Conjugates

Publication ID: 24-11857637_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Novel Applications of Anti-CD25 Antibody-Maytansine Conjugates,” Published Technical Disclosure No. 24-11857637_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857637_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,637.

Summary of the Inventive Concept

This inventive concept explores the application of anti-CD25 antibody-maytansine conjugates in various non-medical fields, including agriculture, environmental monitoring, and personal care, offering novel solutions for crop health monitoring, soil contaminant detection, waterborne pathogen detection, skin condition treatment, and air quality monitoring.

Background and Problem Solved

The original patent disclosed anti-CD25 antibody-maytansine conjugates for therapeutic applications. However, these conjugates have untapped potential in other industries. The inventive concept addresses the limitations of the original patent by exploring new use cases, providing innovative solutions for various industries.

Detailed Description of the Inventive Concept

The new claims describe the application of anti-CD25 antibody-maytansine conjugates in non-medical fields. For instance, claim 1 proposes a system for monitoring crop health by applying the conjugate to plants, which binds to CD25 receptors on plant cells, indicating the health of the plant. Claim 2 describes a method for detecting soil contaminants by adding the conjugate to soil samples, where it binds to CD25 receptors on microorganisms, indicating the presence of contaminants. Similarly, claims 3-5 propose devices and compositions for detecting waterborne pathogens, treating skin conditions, and monitoring air quality, respectively.

Novelty and Inventive Step

The new claims introduce novel applications of anti-CD25 antibody-maytansine conjugates, which are non-obvious and distinct from the original therapeutic applications. The inventive step lies in the unexpected use of these conjugates in non-medical fields, providing innovative solutions for various industries.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include modifying the conjugate structure, using different types of antibodies or maytansinoids, or combining the conjugate with other molecules to enhance its functionality. Variations could include applying the conjugate to different types of plants, soil, or water samples, or using it for detecting other types of contaminants or pathogens.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including agriculture, environmental monitoring, personal care, and healthcare. The market for these applications is substantial, with potential customers including farmers, environmental monitoring agencies, skincare companies, and healthcare providers.

CPC Classifications

SectionClassGroup
A A61 A61K47/6807
C C07 C07K16/2866
A A61 A61K47/65

Original Patent Information

Patent NumberUS 11,857,637
TitleAnti-CD25 antibody-maytansine conjugates and methods of use thereof
Assignee(s)R.P. Scherer Technologies, LLC