Quinone-Containing Conjugates for Diverse Applications
Legal Citation
Summary of the Inventive Concept
The present inventive concept discloses the application of quinone-containing conjugates to novel fields beyond proliferative disorders, including agriculture, medical devices, wastewater treatment, environmental monitoring, and heavy metal remediation.
Background and Problem Solved
The original patent disclosed quinone-containing conjugates for the detection and treatment of proliferative disorders. However, the conjugates' potential extends beyond this scope. The present inventive concept addresses the limitation of the original patent by exploring new applications and use cases for these conjugates, thereby expanding their utility and impact.
Detailed Description of the Inventive Concept
The quinone-containing conjugates of the present inventive concept comprise a cell-binding moiety and a payload. In the new applications, the cell-binding moiety is designed to selectively bind to targets in the respective fields, such as plant-binding peptides in agriculture, anti-biofilm antibodies in medical devices, peptides that selectively bind to pollutants in wastewater treatment, and peptides that selectively bind to heavy metals in environmental remediation. The payload is chosen based on the specific application, including fungicides, bactericides, antimicrobial agents, enzymes, fluorescent labels, and chelating agents.
Novelty and Inventive Step
The present inventive concept's novelty lies in the unexpected application of quinone-containing conjugates to diverse fields beyond proliferative disorders. The inventive step resides in the recognition of the conjugates' potential in these new areas and the design of novel cell-binding moieties and payloads tailored to each application.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept may include the use of different quinone-containing conjugate structures, various cell-binding moieties, or alternative payloads. Variations may also involve the combination of quinone-containing conjugates with other technologies, such as nanoparticles or liposomes, to enhance their efficacy and delivery.
Potential Commercial Applications and Market
The present inventive concept has significant commercial potential in various industries, including agriculture, medical devices, wastewater treatment, environmental monitoring, and heavy metal remediation. The market for these applications is substantial, with opportunities for partnerships, collaborations, and licensing agreements.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K47/6889 |
| A | A61 | A61K31/122 |
| A | A61 | A61K47/6891 |
| A | A61 | A61K49/0039 |
| A | A61 | A61K49/0043 |
| A | A61 | A61K49/0052 |
| C | C07 | C07D417/12 |
| C | C07 | C07K16/30 |
| G | G01 | G01N33/582 |
Original Patent Information
| Patent Number | US 11,857,638 |
|---|---|
| Title | Quinone-containing conjugates |
| Assignee(s) | Promega Corporation |