Synergistic Quinone-Containing Conjugates

Publication ID: 24-11857638_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Quinone-Containing Conjugates,” Published Technical Disclosure No. 24-11857638_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857638_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,638.

Summary of the Inventive Concept

Integrating quinone-containing conjugates with distinct technologies, such as AI, IoT, blockchain, and novel materials, to create a new, more powerful system for detecting and treating proliferative disorders.

Background and Problem Solved

The present disclosure builds upon the original patent's quinone-containing conjugates, which have shown promise in selectively targeting and destroying tumor cells. However, there remains a need to further enhance their efficacy and expand their applicability. The new inventive concept addresses these limitations by combining the conjugates with complementary technologies to create a more robust and versatile system.

Detailed Description of the Inventive Concept

The synergistic quinone-containing conjugates integrate the original conjugates with AI modules to optimize their binding affinity to target antigens, blockchain-based data storage systems to securely store and analyze patient data, IoT devices to monitor and control conjugate administration, and novel materials with enhanced biocompatibility to improve therapeutic efficacy. These combinations enable real-time monitoring, personalized treatment, and enhanced delivery of the conjugates, ultimately leading to improved patient outcomes.

Novelty and Inventive Step

The new claims introduce a synergistic approach that combines the quinone-containing conjugates with distinct technologies, resulting in a novel and non-obvious system that overcomes the limitations of the original patent. The integration of AI, IoT, blockchain, and novel materials provides a unique and innovative solution that enhances the conjugates' efficacy and expands their applicability.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include integrating the quinone-containing conjugates with other technologies, such as machine learning algorithms, nanorobotics, or gene editing tools. Variations could also include modifying the conjugates' structure or composition to optimize their performance in different applications or environments.

Potential Commercial Applications and Market

The synergistic quinone-containing conjugates have significant commercial potential in the fields of oncology, diagnostics, and precision medicine. The system's ability to provide personalized treatment, real-time monitoring, and enhanced delivery could revolutionize the way proliferative disorders are detected and treated, opening up new market opportunities and revenue streams for companies operating in these spaces.

CPC Classifications

SectionClassGroup
A A61 A61K47/6889
A A61 A61K31/122
A A61 A61K47/6891
A A61 A61K49/0039
A A61 A61K49/0043
A A61 A61K49/0052
C C07 C07D417/12
C C07 C07K16/30
G G01 G01N33/582

Original Patent Information

Patent NumberUS 11,857,638
TitleQuinone-containing conjugates
Assignee(s)Promega Corporation