Quinone-Containing Conjugates for Synergistic Combinations

Publication ID: 24-11857638_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Quinone-Containing Conjugates for Synergistic Combinations,” Published Technical Disclosure No. 24-11857638_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857638_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,638.

Summary of the Inventive Concept

This inventive concept integrates quinone-containing conjugates with distinct technologies like AI, IoT, blockchain, and new materials to create a more powerful system for detecting and treating proliferative disorders.

Background and Problem Solved

The original patent disclosed quinone-containing conjugates for detecting and treating proliferative disorders, but it had limitations in terms of efficacy monitoring, supply chain management, and material properties. This new inventive concept addresses these limitations by synergistically combining the conjugates with AI, IoT, blockchain, and new materials.

Detailed Description of the Inventive Concept

The new system comprises a quinone-containing conjugate of formula (I) and an artificial intelligence module for analyzing the conjugate's binding affinity to tumor cells. Additionally, the system can be integrated with IoT-enabled devices for monitoring treatment efficacy, blockchain-based platforms for secure supply chain management, and composite materials comprising biodegradable polymers for targeted cancer therapy. The system can also utilize machine learning algorithms to predict the efficacy of the conjugate in treating proliferative disorders.

Novelty and Inventive Step

The new claims introduce novel synergistic combinations of quinone-containing conjugates with AI, IoT, blockchain, and new materials, which are non-obvious and provide significant improvements over the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept include using different AI algorithms, IoT devices, or blockchain platforms. Variations of the composite material could include different biodegradable polymers or conjugate formulations.

Potential Commercial Applications and Market

The inventive concept has potential commercial applications in the fields of cancer therapy, diagnostics, and pharmaceuticals. The target market includes pharmaceutical companies, research institutions, and hospitals.

CPC Classifications

SectionClassGroup
A A61 A61K47/6889
A A61 A61K31/122
A A61 A61K47/6891
A A61 A61K49/0039
A A61 A61K49/0043
A A61 A61K49/0052
C C07 C07D417/12
C C07 C07K16/30
G G01 G01N33/582

Original Patent Information

Patent NumberUS 11,857,638
TitleQuinone-containing conjugates
Assignee(s)Promega Corporation