Quinone-containing conjugates for specialized applications
Legal Citation
Summary of the Inventive Concept
Adapted quinone-containing conjugates for high-security needs, disaster relief, and extreme weather conditions, providing targeted treatment and detection of proliferative disorders in niche environments.
Background and Problem Solved
The original patent disclosed quinone-containing conjugates for the detection and treatment of proliferative disorders. However, these conjugates lacked features suitable for specific, narrow market or unique operational environments. The present inventive concept addresses this limitation by introducing modified conjugates tailored to high-security needs, disaster relief, and extreme weather conditions.
Detailed Description of the Inventive Concept
The inventive concept involves modifying the quinone-containing conjugates of formula (I) to include features such as tamper-evident cell binding moieties, weather-resistant linkers, and long-shelf-life payloads. These adaptations enable the conjugates to operate effectively in high-security environments, withstand extreme weather conditions, and provide reliable treatment and detection in disaster relief settings. For instance, claim 1 introduces a tamper-evident feature in the cell binding moiety Cb, while claim 2 modifies the linker L1 to include a weather-resistant coating. Claim 3 incorporates a stabilizing agent effective in extreme weather conditions, and claim 4 includes a secure data transmission protocol for high-security environments. Claim 5 features a long-shelf-life component in the payload.
Novelty and Inventive Step
The novelty of the present inventive concept lies in the introduction of specialized features tailored to specific, narrow market or unique operational environments. The inventive step is in recognizing the need for adapted conjugates and implementing modifications that address the limitations of the original patent.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include conjugates with varying levels of security, different weather-resistant coatings, or payloads with adjustable shelf lives. Variations could also involve adapting the conjugates for use in other niche environments, such as high-altitude or underwater applications.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the pharmaceutical and biotechnology industries, particularly in the areas of targeted cancer therapy and diagnostic tools. The adapted conjugates could be marketed to organizations operating in high-security environments, disaster relief agencies, and companies specializing in extreme weather condition applications.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K47/6889 |
| A | A61 | A61K31/122 |
| A | A61 | A61K47/6891 |
| A | A61 | A61K49/0039 |
| A | A61 | A61K49/0043 |
| A | A61 | A61K49/0052 |
| C | C07 | C07D417/12 |
| C | C07 | C07K16/30 |
| G | G01 | G01N33/582 |
Original Patent Information
| Patent Number | US 11,857,638 |
|---|---|
| Title | Quinone-containing conjugates |
| Assignee(s) | Promega Corporation |