Microorganism-based industrial process monitoring and control systems

Publication ID: 24-11857642_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Microorganism-based industrial process monitoring and control systems,” Published Technical Disclosure No. 24-11857642_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857642_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,642.

Summary of the Inventive Concept

The present inventive concept relates to the application of the SYNP161 promoter sequence in microorganism-based systems for monitoring and controlling industrial processes, bioremediation, biosensing, biofuel production, and food safety monitoring.

Background and Problem Solved

The original patent disclosed the SYNP161 promoter sequence for specific expression of genes in rod photoreceptor cells. However, this invention was limited to gene expression in a specific cell type. The new inventive concept addresses the need for a versatile promoter sequence that can be applied to various industrial processes, enabling real-time monitoring and control of microorganisms' metabolic activity.

Detailed Description of the Inventive Concept

The inventive concept utilizes the SYNP161 promoter sequence to drive gene expression in microorganisms, which are then used in various industrial applications. For example, in industrial process monitoring, the microorganism's metabolic activity is monitored to detect changes in the process. In bioremediation, the microorganism is engineered to express a gene that degrades pollutants, and its metabolic activity is monitored to determine the effectiveness of the process. Similarly, in biosensing, the microorganism's metabolic activity is used to detect environmental pollutants. In biofuel production, the microorganism is engineered to express a gene that facilitates fermentation, and its metabolic activity is monitored to optimize biofuel production. In food safety monitoring, the microorganism's metabolic activity is used to detect food contaminants.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious because it applies the SYNP161 promoter sequence to entirely new fields and industries, leveraging its specific gene expression capabilities in microorganisms. The inventive step lies in the recognition of the promoter sequence's potential for industrial applications beyond its original intended use.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different promoter sequences, various microorganism species, or different gene expression systems. Additionally, the inventive concept could be adapted for use in other industries, such as pharmaceuticals or agriculture.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including industrial process monitoring, bioremediation, biosensing, biofuel production, and food safety monitoring. The market for these applications is substantial, with a growing need for efficient and cost-effective solutions.

CPC Classifications

SectionClassGroup
A A61 A61K48/0058
A A61 A61K48/00
C C12 C12N15/63
C C12 C12N15/79
C C12 C12N15/86
C C12 C12N2750/14143
C C12 C12N2830/008

Original Patent Information

Patent NumberUS 11,857,642
TitleSYNP161, a promoter for the expression of genes
Assignee(s)FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH