SYNP161 Variants for High-Security and Extreme Environment Applications
Legal Citation
Summary of the Inventive Concept
Adaptation of SYNP161 promoter for gene expression in rod photoreceptors, tailored for high-security bioresearch facilities, disaster relief scenarios, extreme weather conditions, and remote or isolated research environments.
Background and Problem Solved
The original SYNP161 promoter invention provides a nucleic acid sequence for gene expression in rod photoreceptors, but lacks specific adaptations for specialized markets. The new inventive concept addresses the need for secure, reliable, and adaptable gene expression systems in high-security bioresearch facilities, disaster relief scenarios, extreme weather conditions, and remote or isolated research environments.
Detailed Description of the Inventive Concept
The inventive concept involves adapting the SYNP161 promoter for gene expression in rod photoreceptors to specific operational environments. This includes a system for gene expression in high-security bioresearch facilities, a method for expressing genes in disaster relief scenarios, a vector for gene expression in extreme weather conditions, a kit for gene expression in high-security bioresearch facilities, and a method for gene expression in remote or isolated research environments. Each adaptation incorporates the SYNP161 promoter with additional components and modifications to ensure secure, reliable, and adaptable gene expression.
Novelty and Inventive Step
The new claims introduce novel adaptations of the SYNP161 promoter for specific operational environments, providing a non-obvious solution for secure, reliable, and adaptable gene expression in high-security bioresearch facilities, disaster relief scenarios, extreme weather conditions, and remote or isolated research environments.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include adaptations for other specialized markets, such as high-containment laboratories or emergency response situations. Variations could also involve different vector systems, gene editing tools, or expression cassette designs to further enhance the inventive concept's flexibility and applicability.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the biotechnology and pharmaceutical industries, particularly in the development of gene therapies and vaccines for high-security bioresearch facilities, disaster relief scenarios, extreme weather conditions, and remote or isolated research environments.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K48/0058 |
| A | A61 | A61K48/00 |
| C | C12 | C12N15/63 |
| C | C12 | C12N15/79 |
| C | C12 | C12N15/86 |
| C | C12 | C12N2750/14143 |
| C | C12 | C12N2830/008 |
Original Patent Information
| Patent Number | US 11,857,642 |
|---|---|
| Title | SYNP161, a promoter for the expression of genes |
| Assignee(s) | FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH |