Enhanced Fluorescence Technology for Diverse Applications

Publication ID: 24-11857643_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Enhanced Fluorescence Technology for Diverse Applications,” Published Technical Disclosure No. 24-11857643_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857643_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,643.

Summary of the Inventive Concept

This inventive concept leverages the core technology of enhanced fluorescence to create novel systems, methods, and compositions for various industries, including environmental monitoring, food safety, animal health, industrial process control, and bioterrorism detection.

Background and Problem Solved

The original patent addressed the limitations of fluorescent quenching in biomolecule labeling. However, the technology's potential applications were largely confined to the biomedical field. This inventive concept tackles the challenge of adapting the enhanced fluorescence technology to entirely new industries and use cases, overcoming the limitations of traditional fluorescence-based methods in these domains.

Detailed Description of the Inventive Concept

The inventive concept comprises a range of systems, methods, and compositions that utilize the core technology of enhanced fluorescence to improve detection sensitivity and accuracy in diverse applications. For instance, a system for monitoring environmental pollutants employs fluorescently labeled antibodies conjugated with spacer molecules and fluorescent labels to enhance fluorescence signal and reduce quenching. Similarly, a method for detecting foodborne pathogens involves using fluorescently labeled antibodies with enhanced fluorescence properties to detect pathogens in food samples. Other embodiments include devices for diagnosing diseases in animals, compositions for monitoring industrial processes, and methods for detecting bioterrorism agents.

Novelty and Inventive Step

The inventive concept's novelty lies in its application of the enhanced fluorescence technology to novel industries and use cases, which were not anticipated by the original patent. The inventive step resides in the recognition of the technology's potential to address specific challenges in these new domains and the development of tailored solutions to overcome these challenges.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different types of biomolecules, such as peptides or aptamers, or the incorporation of additional components, such as nanoparticles or graphene, to further enhance fluorescence signals. Variations of the inventive concept could also involve the development of portable or handheld devices for on-site detection and monitoring.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including environmental monitoring, food safety, animal health, industrial process control, and bioterrorism detection. The market for these applications is substantial, with growing demands for more sensitive and accurate detection methods. The inventive concept's ability to provide enhanced fluorescence signals and reduce quenching makes it an attractive solution for companies and organizations operating in these industries.

CPC Classifications

SectionClassGroup
A A61 A61K49/0015
A A61 A61K47/10
A A61 A61K47/18
A A61 A61K49/0058
G G01 G01N33/533
G G01 G01N33/582
G G01 G01N33/68

Original Patent Information

Patent NumberUS 11,857,643
TitleCompositions and methods for enhanced fluorescence
Assignee(s)Life Technologies Corporation, Pierce Biotechnology, Inc.