Specialized Fluorescence Solutions for Niche Environments

Publication ID: 24-11857643_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Fluorescence Solutions for Niche Environments,” Published Technical Disclosure No. 24-11857643_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857643_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,643.

Summary of the Inventive Concept

This inventive concept adapts the original compositions and methods for enhanced fluorescence to specific, narrow markets or unique operational environments, such as high-security needs, disaster relief, extreme weather conditions, forensic analysis, and high-altitude research.

Background and Problem Solved

The original patent disclosed compositions and methods for increasing fluorescent signals and reducing fluorescent quenching. However, the original patent did not address the limitations and challenges of implementing these compositions and methods in specialized environments, such as high-security biometric applications, disaster relief operations, extreme weather conditions, forensic analysis, and high-altitude research. The new inventive concept addresses these limitations by adapting the original compositions and methods to these specific environments.

Detailed Description of the Inventive Concept

The new inventive concept comprises specialized spacer molecules that are resistant to tampering and alteration, extreme environmental conditions, temperature fluctuations and humidity, contamination and degradation, and low oxygen levels and high pressure. These spacer molecules are conjugated to fluorescently labeled biomolecules, such as antibodies, DNA, and proteins, to enhance fluorescent signals and reduce quenching in these specific environments. The new inventive concept also includes methods for increasing fluorescent signals and reducing quenching in these environments, as well as compositions for fluorescent imaging and systems for enhanced fluorescence.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious because it adapts the original compositions and methods to specific, narrow markets or unique operational environments, which were not addressed in the original patent. The use of specialized spacer molecules and the adaptation of the original compositions and methods to these environments are new and non-obvious.

Alternative Embodiments and Variations

Alternative embodiments of the new inventive concept could include the use of different types of spacer molecules, such as those that are resistant to radiation or electromagnetic interference. Other variations could include the use of different types of fluorescent labels or biomolecules, such as quantum dots or nanoparticles.

Potential Commercial Applications and Market

The new inventive concept has commercial potential in various industries, including biotechnology, forensic analysis, disaster relief, and high-altitude research. The specialized spacer molecules and adapted compositions and methods could be used in a variety of applications, such as high-security biometric identification, disaster relief operations, and forensic analysis.

CPC Classifications

SectionClassGroup
A A61 A61K49/0015
A A61 A61K47/10
A A61 A61K47/18
A A61 A61K49/0058
G G01 G01N33/533
G G01 G01N33/582
G G01 G01N33/68

Original Patent Information

Patent NumberUS 11,857,643
TitleCompositions and methods for enhanced fluorescence
Assignee(s)Life Technologies Corporation, Pierce Biotechnology, Inc.