Near-Infrared Fluorescence-Based Sensing and Monitoring Systems

Publication ID: 24-11857645_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Near-Infrared Fluorescence-Based Sensing and Monitoring Systems,” Published Technical Disclosure No. 24-11857645_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857645_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,645.

Summary of the Inventive Concept

The present inventive concept leverages the core technology of near IR, closed chain, sulfo-cyanine dyes and ligands to create novel sensing and monitoring systems for various industries, including agriculture, environmental monitoring, food safety, and air quality control.

Background and Problem Solved

The original patent focused on compositions for medical imaging, but the core technology has broader applications. The present inventive concept addresses the need for efficient, non-invasive, and accurate sensing and monitoring solutions in various industries, where traditional methods are often limited by cost, complexity, or accuracy.

Detailed Description of the Inventive Concept

The inventive concept involves the use of near IR, closed chain, sulfo-cyanine dyes and ligands to create compositions that bind to specific targets in various industries, emitting fluorescence upon near-infrared radiation excitation. The systems comprise a near-infrared radiation source, a sensor or camera, and the composition. The fluorescence signal is detectable by the sensor or camera, allowing for real-time monitoring and detection of targets. For example, in agriculture, the composition can bind to stressed or diseased crops, enabling early detection and targeted intervention. Similarly, in environmental monitoring, the composition can bind to pollutants, enabling tracking and identification of pollution sources.

Novelty and Inventive Step

The new claims introduce novel applications and use cases for the core technology, including sensing and monitoring systems for agriculture, environmental monitoring, food safety, and air quality control. The inventive step lies in the adaptation of the original technology to these new industries, enabling innovative solutions for pressing problems.

Alternative Embodiments and Variations

Alternative embodiments may include different ligand designs, varying near-infrared radiation sources, or modified sensor architectures. Variations could include handheld devices for point-of-use monitoring or large-scale, networked systems for widespread surveillance.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including agriculture, environmental monitoring, food safety, and air quality control. The market size for these industries is substantial, with growing demand for innovative, efficient, and accurate sensing and monitoring solutions. The inventive concept offers a unique value proposition, enabling early detection, targeted intervention, and improved decision-making.

CPC Classifications

SectionClassGroup
A A61 A61K49/0052
A A61 A61K9/0019
A A61 A61K49/0032
A A61 A61K49/0034
C C09 C09B23/0025
C C09 C09B23/0066
G G01 G01N33/57434

Original Patent Information

Patent NumberUS 11,857,645
TitleCompositions of near IR closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands
Assignee(s)INTUITIVE SURGICAL OPERATIONS, INC.