Specialized Ultrasound Contrast Agents for Niche Environments

Publication ID: 24-11857646_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Ultrasound Contrast Agents for Niche Environments,” Published Technical Disclosure No. 24-11857646_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857646_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,646.

Summary of the Inventive Concept

Improved methods for preparing phospholipid-based ultrasound contrast agents tailored for high-security, disaster relief, extreme weather, remote, and high-altitude environments.

Background and Problem Solved

The original patent disclosed improved methods for preparing phospholipid-based ultrasound contrast agents. However, these methods may not be suitable for specific, narrow markets or unique operational environments. The new inventive concept addresses this limitation by adapting the original methods to cater to these niche environments, ensuring reliable and efficient ultrasound imaging in challenging situations.

Detailed Description of the Inventive Concept

The new inventive concept comprises systems, methods, and devices for preparing ultrasound contrast agents in specialized environments. For high-security environments, a mechanism for monitoring and controlling divalent metal cation levels is integrated into the phospholipid solution. In disaster relief situations, a portable ultrasound device is paired with a calcium-resistant phospholipid blend. For extreme weather conditions, a temperature-controlled chamber maintains optimal reaction conditions. In remote or resource-limited areas, a solar-powered ultrasound device is used. Finally, for high-altitude environments, a low-oxygen-tolerant phospholipid blend is employed in a pressurized reaction chamber. These adaptations ensure the reliable preparation of ultrasound contrast agents in diverse, challenging environments.

Novelty and Inventive Step

The new claims introduce novel adaptations to the original patent's methods, enabling the preparation of ultrasound contrast agents in niche environments. The inventive step lies in the integration of specialized components, such as mechanisms for monitoring divalent metal cation levels, portable ultrasound devices, temperature-controlled chambers, solar-powered ultrasound devices, and pressurized reaction chambers, which were not contemplated in the original patent.

Alternative Embodiments and Variations

Alternative embodiments could include the use of different phospholipid blends, alternative solvents, or modified reaction conditions. Additionally, the inventive concept could be implemented using different materials, such as biodegradable or biocompatible materials, or integrated with other medical imaging modalities.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in various industries, including medical imaging, disaster relief, and environmental monitoring. The ability to prepare ultrasound contrast agents in niche environments opens up new markets and opportunities for medical imaging applications in challenging situations.

CPC Classifications

SectionClassGroup
A A61 A61K49/223
A A61 A61B8/481
A A61 A61K49/226
A A61 A61K49/227
C C07 C07F9/09
C C07 C07F9/106

Original Patent Information

Patent NumberUS 11,857,646
TitleMethods for making ultrasound contrast agents
Assignee(s)Lantheus Medical Imaging, Inc.