Multivalent Molecule-Based Solutions for Diverse Industries
Legal Citation
Summary of the Inventive Concept
This inventive concept expands the core technology of multivalent molecules to tackle diverse problems in agriculture, environmental monitoring, medical devices, and water quality, offering targeted solutions for pest control, fungal infection detection, biofilm treatment, and pollutant monitoring.
Background and Problem Solved
The original patent focused on molecular imaging and radioimmunotherapy, but its multivalent molecule technology has broader potential. This inventive concept addresses the limitations of existing solutions in various industries by leveraging the versatility of multivalent molecules to target specific biomarkers, enabling precise detection and treatment of diverse problems.
Detailed Description of the Inventive Concept
The inventive concept involves designing multivalent molecules with a first peptide and a chelator, which can be loaded with a pesticide, detectable label, or other payloads. A second peptide targets specific biomarkers in various industries, such as agricultural pests, fungal infections in plants, waterborne pathogens, biofilm-forming microorganisms, or environmental pollutants. The multivalent molecule's modular design enables easy adaptation to different applications, ensuring precise detection and treatment of targeted problems.
Novelty and Inventive Step
The new claims introduce a paradigm shift by applying the core multivalent molecule technology to entirely new industries and use cases, demonstrating a non-obvious expansion of the original patent's scope. The inventive step lies in the recognition of the technology's versatility and its adaptation to diverse problem domains.
Alternative Embodiments and Variations
Alternative embodiments could involve varying the chelator, peptide sequences, or payload types to suit specific industry requirements. Variations may include using different detectable labels, such as fluorescent dyes or radiolabels, or incorporating additional components to enhance targeting efficiency or payload delivery.
Potential Commercial Applications and Market
This inventive concept has significant commercial potential in various industries, including agriculture, environmental monitoring, medical devices, and water quality management. The market demand for targeted solutions in these areas is substantial, and the inventive concept's versatility and adaptability make it an attractive opportunity for companies seeking to address diverse challenges.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K51/082 |
| A | A61 | A61K9/51 |
| A | A61 | A61K47/6893 |
| A | A61 | A61K51/1027 |
| C | C07 | C07D255/02 |
| C | C07 | C07D257/02 |
| C | C07 | C07K7/06 |
| C | C07 | C07K7/64 |
| C | C07 | C07K16/30 |
| G | G01 | G01N33/5008 |
| G | G01 | G01N33/60 |
| C | C07 | C07K2319/00 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Molecular imaging, targeted drug delivery, and biomarker detection technologies, encompassing biochemistry, molecular biology, and chemical engineering with expertise in peptide design, chelator chemistry, and diagnostic/therapeutic molecular systems
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in chemistry or molecular biology, experienced in designing multivalent molecular constructs, familiar with chelator chemistry, radiolabeling techniques, and biomarker targeting strategies
Obviousness Rationale
A PHOSITA would recognize the source patent's multivalent molecular imaging technology as a versatile platform that could be readily adapted to diverse application domains by systematically substituting targeting peptides, payloads, and detection modalities while maintaining the core molecular architecture and dimerization strategies disclosed in the original patent.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,648 |
|---|---|
| Title | Dimerization strategies and compounds for molecular imaging and/or radioimmunotherapy |
| Assignee(s) | UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |