Expanding Calcium-Fluoride Technology to Novel Industries

Publication ID: 24-11857653_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Expanding Calcium-Fluoride Technology to Novel Industries,” Published Technical Disclosure No. 24-11857653_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857653_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,653.

Summary of the Inventive Concept

This inventive concept explores the application of the calcium-fluoride technology, originally developed for oral care, to new industries and use cases, including skin care, hair care, nail care, wound healing, and respiratory treatment.

Background and Problem Solved

The original patent disclosed a method for providing an oral care benefit using a poorly-soluble calcium compound and fluoride. However, the technology's potential was limited to oral care applications. This inventive concept addresses the need for expanding this technology to other industries, where calcium-bound fluoride deposits can provide benefits such as skin hydration, hair growth, nail fungus treatment, wound healing, and respiratory treatment.

Detailed Description of the Inventive Concept

The new inventive concept involves applying the calcium-fluoride technology to various industries, including skin care, hair care, nail care, wound healing, and respiratory treatment. In skin care, the poorly-soluble calcium compound is applied to the skin, followed by a topical fluoride treatment to promote calcium-bound fluoride deposits, enhancing skin hydration and reducing inflammation. In hair care, the calcium compound is introduced to the scalp, and a fluoride-containing hair care product is applied to stimulate hair growth and strengthen hair follicles. In nail care, a composition comprising a poorly-soluble calcium compound and a fluoride source is used to inhibit fungal growth. In wound healing, the calcium compound is applied to the wound site, followed by a fluoride-containing wound dressing to promote calcium-bound fluoride deposits and enhance tissue repair. In respiratory treatment, the calcium compound is inhaled, followed by a fluoride-containing aerosol to promote calcium-bound fluoride deposits in the lungs, reducing inflammation and improving lung function.

Novelty and Inventive Step

The new claims introduce a novel application of the calcium-fluoride technology to industries beyond oral care, demonstrating an inventive step by leveraging the original patent's concept to address new problems and needs.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include varying the formulation of the poorly-soluble calcium compound, adjusting the timing and sequence of the calcium and fluoride applications, or exploring different delivery methods for the calcium and fluoride components.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including skin care, hair care, nail care, wound healing, and respiratory treatment. The target market includes companies developing products and treatments for these industries, as well as consumers seeking innovative solutions for these applications.

CPC Classifications

SectionClassGroup
A A61 A61K8/21
A A61 A61K8/0204
A A61 A61K8/0216
A A61 A61K8/19
A A61 A61K8/24
A A61 A61K8/44
A A61 A61Q11/00

Field of Art

Medical and pharmaceutical compositions involving calcium compounds and fluoride treatments, with expertise in oral care, topical applications, and targeted delivery systems across dermatological, hair care, wound healing, and respiratory treatment domains

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in pharmaceutical sciences, chemistry, or biomedical engineering, possessing knowledge of compound interactions, delivery mechanisms, and cross-industry therapeutic applications

Obviousness Rationale

A PHOSITA would recognize the fundamental calcium-fluoride interaction mechanism disclosed in the source patent as fundamentally transferable across biological systems, understanding that the core chemical principle of creating calcium-bound fluoride deposits represents a generalizable therapeutic approach applicable to multiple physiological contexts beyond oral care.

Obvious Combinations & Variations

Source Patent Element
Method of administering poorly-soluble calcium compound followed by fluoride to create calcium-bound fluoride deposits
PTD Variation
Applying the same methodology to skin, scalp, wound sites, and respiratory systems
Obviousness Reasoning
Predictable extension of known chemical interaction principle to analogous biological surfaces with similar molecular interaction potential
Source Patent Element
Specific timing windows for calcium and fluoride introduction (within 30 minutes to 12 hours)
PTD Variation
Maintaining consistent timing protocols across different application domains
Obviousness Reasoning
Known technique of preserving successful interaction parameters when translating between biological contexts
Source Patent Element
Use of calcium compounds like calcium phosphate, calcium carbonate
PTD Variation
Selecting equivalent calcium compounds for diverse tissue interactions
Obviousness Reasoning
Design choice based on established chemical compatibility and predictable molecular behavior
Source Patent Element
Targeting oral cavity for remineralization and anti-caries benefits
PTD Variation
Extending remineralization concept to skin hydration, wound healing, and tissue repair
Obviousness Reasoning
Finite set of identifiable therapeutic goals using consistent molecular interaction strategy
Source Patent Element
Fluoride as reactive agent creating deposit formations
PTD Variation
Leveraging fluoride's reactive properties across multiple biological systems
Obviousness Reasoning
Well-understood chemical principle of using fluoride as a consistent therapeutic agent with broad applicability
35 U.S.C. § 103 Summary: Based on US Patent 11857653's disclosure of calcium-fluoride interaction methodology, the present publication demonstrates that a person of ordinary skill in the art would find the extension of said methodology to diverse biological systems an obvious variation, rendering potential claims to such applications anticipated and non-patentable under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,857,653
TitleMethod of providing an oral care benefit using a poorly-soluble calcium compound and fluoride
Assignee(s)Johnson & Johnson Consumer Inc.