Enhanced NHAP Containing Oral Composition with Improved Bioavailability and Shelf Life

Publication ID: 24-11857654_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced NHAP Containing Oral Composition with Improved Bioavailability and Shelf Life,” Published Technical Disclosure No. 24-11857654_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857654_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,654.

Summary of the Inventive Concept

An innovative oral composition containing nanohydroxyapatite (NHAP) with enhanced bioavailability and extended shelf life, offering improved oral care benefits and user convenience.

Background and Problem Solved

The original patent disclosed an alkaline dental composition containing NHAP, free of glycerin, fluoride, and a surfactant. However, it had limitations in terms of bioavailability, shelf life, and user experience. The new inventive concept addresses these limitations by incorporating a flavoring agent that enhances NHAP bioavailability, stabilizing the composition with a pH buffering agent, and introducing a dispensing system with a built-in timer.

Detailed Description of the Inventive Concept

The enhanced oral composition comprises a NHAP suspension stock with a particle size of less than 100 nanometers, increasing the surface area for improved remineralization. The composition is further stabilized with a pH buffering agent, extending the shelf life to at least 5 years. Additionally, a flavoring agent is incorporated to enhance NHAP bioavailability, and a mild abrasive can be added to improve whitening efficacy. A novel dispensing system features a container with a built-in timer, alerting the user when the product is approaching its expiration date, ensuring safe and effective use.

Novelty and Inventive Step

The new claims introduce several novel and non-obvious features, including the use of a flavoring agent to enhance NHAP bioavailability, the incorporation of a pH buffering agent to extend shelf life, and the development of a dispensing system with a built-in timer. These innovations provide significant improvements over the original patent, offering enhanced oral care benefits, user convenience, and product safety.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include varying the particle size of the NHAP suspension stock, using different flavoring agents or mild abrasives, or incorporating additional ingredients to enhance oral care benefits. The dispensing system could also be modified to include additional features, such as a dosage tracker or a reminder system.

Potential Commercial Applications and Market

The enhanced NHAP containing oral composition has significant commercial potential in the oral care industry, particularly in the development of premium toothpaste products with improved efficacy and user convenience. The target market includes health-conscious consumers seeking high-quality oral care products with advanced features and benefits.

CPC Classifications

SectionClassGroup
A A61 A61K8/24
A A61 A61K8/19
A A61 A61K8/922
A A61 A61Q11/00
A A61 A61K2800/413
A A61 A61K2800/87
A A61 A61K2800/92

Field of Art

Dental care compositions, specifically oral hygiene products with nanohydroxyapatite (NHAP) formulations, involving materials science, pharmaceutical chemistry, and oral health technologies

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degree in materials science, chemistry, or pharmaceutical sciences, with expertise in dental product formulation, nanotechnology, and oral care product development, familiar with particle engineering and composition optimization

Obviousness Rationale

A PHOSITA would recognize that the PTD's variations represent predictable extensions of the source patent's core NHAP composition, utilizing standard pharmaceutical engineering techniques to incrementally improve oral care product performance through particle size optimization, shelf-life enhancement, and functional additives.

Obvious Combinations & Variations

Source Patent Element
NHAP suspension stock in dental composition
PTD Variation
Reducing NHAP particle size to less than 100 nanometers to increase surface area
Obviousness Reasoning
Particle size reduction is a known technique for enhancing material reactivity and bioavailability, representing a predictable optimization approach for a skilled formulation scientist
Source Patent Element
Basic dental composition with sweeteners and NHAP
PTD Variation
Adding flavoring agent to enhance NHAP bioavailability
Obviousness Reasoning
Incorporating flavor compounds to improve ingredient interaction is a standard pharmaceutical formulation strategy with expected and predictable results
Source Patent Element
Dental product with defined composition
PTD Variation
Adding pH buffering agent to extend shelf life to 5 years
Obviousness Reasoning
Shelf-life extension through pH stabilization is a routine pharmaceutical engineering approach using well-understood chemical preservation techniques
Source Patent Element
Basic dental product packaging
PTD Variation
Container with built-in expiration timer
Obviousness Reasoning
User-interface improvements for product safety are common design choices in consumer healthcare products, representing an obvious user experience enhancement
Source Patent Element
NHAP-based dental composition
PTD Variation
Incorporating mild abrasive for enhanced whitening
Obviousness Reasoning
Combining remineralization agents with mechanical whitening components is a standard approach in dental product development with predictable performance improvements
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857654, a person having ordinary skill in the art would find the variations disclosed in the present technical publication to represent obvious modifications to the prior art, employing standard pharmaceutical engineering techniques to incrementally improve NHAP-based oral care compositions through predictable formulation and design strategies.

Original Patent Information

Patent NumberUS 11,857,654
TitleNHAP containing oral composition