Enhanced Antimicrobial Compositions with Modified Clay Particles and Nonionic Triblock Copolymers

Publication ID: 24-11857655_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Antimicrobial Compositions with Modified Clay Particles and Nonionic Triblock Copolymers,” Published Technical Disclosure No. 24-11857655_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857655_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,655.

Summary of the Inventive Concept

The present inventive concept relates to improved antimicrobial compositions comprising modified clay particles with selectively attached antimicrobial compounds on one exterior surface plane, resulting in enhanced antimicrobial properties and improved stability.

Background and Problem Solved

The original patent disclosed antimicrobial compositions comprising modified clay particles and nonionic triblock copolymers. However, the existing patent had limitations in terms of antimicrobial efficacy, stability, and dispersibility. The new inventive concept addresses these limitations by introducing modified clay particles with selectively attached antimicrobial compounds on one exterior surface plane, leading to improved antimicrobial properties and stability.

Detailed Description of the Inventive Concept

The enhanced antimicrobial compositions comprise modified clay particles with asymmetric 1:1 or 2:1:1 clay particle structure, having alternating tetrahedral and octahedral sheets terminating with a tetrahedral and an octahedral sheet at exterior surface planes. The antimicrobial compound is selectively attached to coordinating cations on only one exterior surface plane, resulting in improved antimicrobial efficacy. The compositions further comprise nonionic triblock copolymers with improved compatibility with the modified clay particles, enhancing dispersibility and stability. The modified clay particles can be prepared through a process involving the preparation of a precursor with bipolar topospecific characteristics, selective attachment of the antimicrobial compound, and subsequent treatment to enhance stability and antimicrobial efficacy.

Novelty and Inventive Step

The new inventive concept introduces the novelty of selectively attaching antimicrobial compounds on one exterior surface plane of the modified clay particles, resulting in improved antimicrobial properties and stability. This is a non-obvious improvement over the original patent, as it requires a specific understanding of the clay particle structure and the attachment of antimicrobial compounds.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept include modifying the clay particle structure, using different types of antimicrobial compounds, or incorporating additional components to enhance the antimicrobial properties. Variations of the process for preparing the modified clay particles can also be explored, such as using different precursors or attachment methods.

Potential Commercial Applications and Market

The enhanced antimicrobial compositions have potential commercial applications in personal care products, such as soaps, lotions, and creams, as well as in medical devices, wound care, and food packaging. The target market includes companies operating in the personal care, medical, and food industries, seeking to improve the antimicrobial properties of their products.

CPC Classifications

SectionClassGroup
A A61 A61K8/25
A A61 A61K8/416
A A61 A61K8/86
A A61 A61Q11/00

Field of Art

Personal care and antimicrobial compositions, specifically involving modified clay particles and surface-modified materials with a focus on pharmaceutical and cosmetic applications. Requires expertise in materials science, surface chemistry, and colloidal systems

Person of Ordinary Skill (PHOSITA) Profile

A materials scientist or chemical engineer with advanced degree, specialized knowledge in clay particle modification, surface chemistry techniques, and antimicrobial composition design. Familiar with nonionic triblock copolymer interactions and clay particle structural modifications

Obviousness Rationale

A PHOSITA would recognize that selectively attaching antimicrobial compounds to specific surface planes of asymmetric clay particles represents a predictable engineering optimization of the source patent's core technology. The disclosed variations demonstrate standard problem-solving approaches in materials design, involving strategic modification of particle surface characteristics to enhance antimicrobial performance. The combination of known elements (clay structure, antimicrobial attachment, triblock copolymer compatibility) represents incremental technical advancement rather than non-obvious innovation.

Obvious Combinations & Variations

Source Patent Element
Asymmetric 1:1 or 2:1:1 clay particle with alternating tetrahedral and octahedral sheets
PTD Variation
Selective antimicrobial compound attachment to only one exterior surface plane
Obviousness Reasoning
Predictable surface modification technique using known coordinating cation attachment methods, representing a routine design optimization of particle surface chemistry
Source Patent Element
Antimicrobial composition with clay particles
PTD Variation
Incorporation of nonionic triblock copolymers to enhance dispersibility and compatibility
Obviousness Reasoning
Known technique for improving colloidal stability and particle interaction, representing a standard approach to enhancing composition performance
Source Patent Element
Clay:antimicrobial compound ratio between 1:0.001 to 1:0.1
PTD Variation
Modified attachment strategy focusing on single surface plane attachment
Obviousness Reasoning
Finite set of possible attachment configurations, representing an obvious variation exploring known compositional parameters
Source Patent Element
Antimicrobial compound attached to coordinating cations
PTD Variation
Bipolar topospecific precursor preparation with selective surface attachment
Obviousness Reasoning
Routine materials science approach to controlling particle surface chemistry through established synthetic techniques
Source Patent Element
Poloxamer-based nonionic triblock copolymer
PTD Variation
Enhanced compatibility formulation with modified clay particles
Obviousness Reasoning
Predictable materials engineering solution using known polymer interaction principles to improve composition performance
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857655, the present published technical disclosure demonstrates that the claimed variations in antimicrobial composition design represent obvious extensions of prior art, employing standard materials science techniques to optimize clay particle surface modification and antimicrobial performance. A person having ordinary skill in the art would find the disclosed innovations predictable and within the established technological capabilities of the field, thus rendering potential patent claims obvious and unpatentable under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,655
TitleAntimicrobial compositions comprising modified clay and nonionic triblock copolymers
Assignee(s)Conopco, Inc.