Enhanced Antimicrobial Compositions with Modified Clay Particles and Nonionic Triblock Copolymers
Legal Citation
Summary of the Inventive Concept
The present inventive concept relates to improved antimicrobial compositions comprising modified clay particles with selectively attached antimicrobial compounds on one exterior surface plane, resulting in enhanced antimicrobial properties and improved stability.
Background and Problem Solved
The original patent disclosed antimicrobial compositions comprising modified clay particles and nonionic triblock copolymers. However, the existing patent had limitations in terms of antimicrobial efficacy, stability, and dispersibility. The new inventive concept addresses these limitations by introducing modified clay particles with selectively attached antimicrobial compounds on one exterior surface plane, leading to improved antimicrobial properties and stability.
Detailed Description of the Inventive Concept
The enhanced antimicrobial compositions comprise modified clay particles with asymmetric 1:1 or 2:1:1 clay particle structure, having alternating tetrahedral and octahedral sheets terminating with a tetrahedral and an octahedral sheet at exterior surface planes. The antimicrobial compound is selectively attached to coordinating cations on only one exterior surface plane, resulting in improved antimicrobial efficacy. The compositions further comprise nonionic triblock copolymers with improved compatibility with the modified clay particles, enhancing dispersibility and stability. The modified clay particles can be prepared through a process involving the preparation of a precursor with bipolar topospecific characteristics, selective attachment of the antimicrobial compound, and subsequent treatment to enhance stability and antimicrobial efficacy.
Novelty and Inventive Step
The new inventive concept introduces the novelty of selectively attaching antimicrobial compounds on one exterior surface plane of the modified clay particles, resulting in improved antimicrobial properties and stability. This is a non-obvious improvement over the original patent, as it requires a specific understanding of the clay particle structure and the attachment of antimicrobial compounds.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept include modifying the clay particle structure, using different types of antimicrobial compounds, or incorporating additional components to enhance the antimicrobial properties. Variations of the process for preparing the modified clay particles can also be explored, such as using different precursors or attachment methods.
Potential Commercial Applications and Market
The enhanced antimicrobial compositions have potential commercial applications in personal care products, such as soaps, lotions, and creams, as well as in medical devices, wound care, and food packaging. The target market includes companies operating in the personal care, medical, and food industries, seeking to improve the antimicrobial properties of their products.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K8/25 |
| A | A61 | A61K8/416 |
| A | A61 | A61K8/86 |
| A | A61 | A61Q11/00 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Personal care and antimicrobial compositions, specifically involving modified clay particles and surface-modified materials with a focus on pharmaceutical and cosmetic applications. Requires expertise in materials science, surface chemistry, and colloidal systems
Person of Ordinary Skill (PHOSITA) Profile
A materials scientist or chemical engineer with advanced degree, specialized knowledge in clay particle modification, surface chemistry techniques, and antimicrobial composition design. Familiar with nonionic triblock copolymer interactions and clay particle structural modifications
Obviousness Rationale
A PHOSITA would recognize that selectively attaching antimicrobial compounds to specific surface planes of asymmetric clay particles represents a predictable engineering optimization of the source patent's core technology. The disclosed variations demonstrate standard problem-solving approaches in materials design, involving strategic modification of particle surface characteristics to enhance antimicrobial performance. The combination of known elements (clay structure, antimicrobial attachment, triblock copolymer compatibility) represents incremental technical advancement rather than non-obvious innovation.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,655 |
|---|---|
| Title | Antimicrobial compositions comprising modified clay and nonionic triblock copolymers |
| Assignee(s) | Conopco, Inc. |